Ding Ping, Qi Lingyan, Wang Jinglei, Tang Min, Weng Yujie
Health Management Center, Ningbo Rehabilitation Hospital, Ningbo, Zhejiang, China.
Gynecology Department, Ningbo Rehabilitation Hospital, Ningbo, Zhejiang, China.
Front Endocrinol (Lausanne). 2025 May 5;16:1499381. doi: 10.3389/fendo.2025.1499381. eCollection 2025.
We aimed to examine patterns of diabetes and kidney disease due to Low physical activity (LPA) in 204 countries between 1990 and 2021.
Data were from the Global Burden of Disease (GBD) 2021. Age-standardized death rate (ASDR) and age standardized disability-adjusted life years (DALYs) were estimated. In addition, annual percentage changes (EAPC) were calculated.
The age-standardized DALY rate (EAPC = 0.89; 95% CI: 0.85, 0.93) and age-standardized death rate (ASDR) of diabetes and kidney disease due to LPA increased (EAPC = 0.34; 95% CI: 0.28,0.39) during 1990 to 2021. Among them, the age-standardized DALY rate and ASDR increased fastest in Eastern Europe (EAPC 2.43 and 3.79, respectively). Mauritius had the most significant increase in age-standardized DALY (EAPC = 3.40), while the Russian Federation had the most significant increase in ASDR (EAPC = 4.40). In 2021, both ASDR and age-standardized DALY rates per 100,000 people increased in women compared with men. The age-standardized DALY rate per 100,000 people generally showed an upward trend, with the highest in Oceania (285.33) and the highest ASDR in Southern Sub-Saharan Africa (10.56).
The global ASDR and age-standardized DALY rates reveal a significant surge in diabetes and kidney disease attributable to LPA from 1990 to 2021. This escalation is evident across 21 regions, with notable increases observed in Eastern Europe, Sub-Saharan Africa, and Oceania.
我们旨在研究1990年至2021年间204个国家因身体活动不足（LPA）导致的糖尿病和肾脏疾病模式。
数据来自《2021年全球疾病负担》（GBD 2021）。估计了年龄标准化死亡率（ASDR）和年龄标准化残疾调整生命年（DALYs）。此外，还计算了年度百分比变化（EAPC）。
1990年至2021年间，因LPA导致的糖尿病和肾脏疾病的年龄标准化DALY率（EAPC = 0.89；95% CI：0.85，0.93）和年龄标准化死亡率（ASDR）有所上升（EAPC = 0.34；95% CI：0.28，0.39）。其中，东欧的年龄标准化DALY率和ASDR上升最快（EAPC分别为2.43和3.79）。毛里求斯的年龄标准化DALY增幅最大（EAPC = 3.40），而俄罗斯联邦的ASDR增幅最大（EAPC = 4.40）。2021年，与男性相比，女性每10万人的ASDR和年龄标准化DALY率均有所上升。每10万人的年龄标准化DALY率总体呈上升趋势，大洋洲最高（285.33），撒哈拉以南非洲南部的ASDR最高（10.56）。
全球ASDR和年龄标准化DALY率显示，1990年至2021年间，因LPA导致的糖尿病和肾脏疾病显著增加。这种上升在21个地区都很明显，东欧、撒哈拉以南非洲和大洋洲的增幅尤为显著。
