Zhang Sha, Deng Yao, Xiang Xiaorun, Xu Qianfeng, Hu Lixin, Xia Mei, Liu Lei
Department of Thoracic Surgery, The First Affiliated Hospital of the Army Medical University, Chongqing, China.
Department of Rheumatology and Immunology, The First Affiliated Hospital of the Army Medical University, Chongqing, China.
BMC Pulm Med. 2025 May 20;25(1):244. doi: 10.1186/s12890-025-03711-z.
To investigate the incidence and severity of symptoms in postoperative non-small-cell lung cancer patients undergoing thoracoscopic surgery, construct a symptom network, and analyze centrality indicators of the network to identify core symptoms and provide a basis for precise symptom management.
A convenience sampling method was used to select postoperative NSCLC patients from the Department of Thoracic Surgery at the First Affiliated Hospital of Army Medical University between September 2024 and December 2024. The Chinese version of the Anderson Symptom Inventory Core Symptom Module and the revised Lung Cancer-Specific Symptom Module were used to survey the incidence and severity of symptoms. A symptom network was constructed with R software with the EBICgloss function and Spearman correlation analysis, and the centrality indicators were then calculated.
In total, 404 questionnaires were distributed, and 367 valid questionnaires were returned (effective response rate, 90.8%). The top three symptoms in terms of incidence and severity during the postoperative hospitalization of NSCLC patients were pain (100%), fatigue (99%), and shortness of breath (98%). The results of the centrality indicators of the symptom network revealed that the top three symptoms in terms of strength centrality were shortness of breath (rs = 5.44), fatigue (rs = 5.43), and pain (rs = 5.34).
Postoperative NSCLC patients experience various symptoms, with shortness of breath being the core symptom. Targeted intervention strategies are needed to improve the efficiency and accuracy of symptom management, reduce the symptom burden on patients, and increase their quality of life.
Chinese Clinical Trial Registry (NO. ChiCTR2500096720), registered on 5 February 2025, retrospectively registered.
调查接受胸腔镜手术的非小细胞肺癌患者术后症状的发生率和严重程度，构建症状网络，并分析网络的中心性指标以识别核心症状，为精准症状管理提供依据。
采用便利抽样法，选取陆军军医大学第一附属医院胸外科2024年9月至2024年12月期间的术后非小细胞肺癌患者。使用中文版安德森症状量表核心症状模块和修订后的肺癌特异性症状模块来调查症状的发生率和严重程度。使用R软件的EBICgloss函数和Spearman相关性分析构建症状网络，然后计算中心性指标。
共发放问卷404份，回收有效问卷367份（有效回收率90.8%）。非小细胞肺癌患者术后住院期间发生率和严重程度排名前三的症状为疼痛（100%）、疲劳（99%）和气短（98%）。症状网络的中心性指标结果显示，强度中心性排名前三的症状为气短（rs = 5.44）、疲劳（rs = 5.43）和疼痛（rs = 5.34）。
非小细胞肺癌术后患者会出现多种症状，其中气短是核心症状。需要有针对性的干预策略来提高症状管理的效率和准确性，减轻患者的症状负担，提高其生活质量。
中国临床试验注册中心（编号：ChiCTR2500096720），于2025年2月5日注册，回顾性注册。
