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年龄对术后麻醉后护理单元中肺癌根治术后 24 小时中重度疼痛的影响:一项单中心回顾性队列研究。

Effect of age on postoperative 24-hour moderate-to-severe pain after radical resection of lung cancer-specific pain in the post-anaesthesia care unit: a single-centre retrospective cohort study.

机构信息

Department of Anesthesiology and Perioperative Medicine, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.

Department of Anesthesiology and Perioperative Medicine, Henan University People's Hospital, Zhengzhou, Henan, China.

出版信息

BMJ Open. 2024 Aug 17;14(8):e085702. doi: 10.1136/bmjopen-2024-085702.

Abstract

OBJECTIVES

To explore the relationship between age and postoperative 24-hour moderate-to-severe pain after radical resection of lung cancer and the specific effect of moderate-to-severe pain in the post-anaesthesia care unit (PACU) on this relationship.

DESIGN

Retrospective cohort study.

SETTING

Single medical centre.

PARTICIPANTS

Patients ≥18 years having radical resection of lung cancer between 2018 and 2020.

MEASUREMENTS

Postoperative 24-hour moderate-to-severe pain.

RESULTS

A total of 3764 patients were included in the analysis. The incidence of postoperative 24-hour moderate-to-severe pain was 28.3%. Age had a significant effect on the prediction model of postoperative 24-hour moderate-to-severe pain. Among the whole population and those without moderate-to-severe pain in the PACU, those who were younger than 58.5 years were prone to experience moderate-to-severe pain 24 hours after surgery, and in patients with moderate-to-severe pain in the PACU, the age threshold was 62.5 years.

CONCLUSION

For patients who underwent elective radical resection for lung cancer, age was related to postoperative 24-hour moderate-to-severe pain, and moderate-to-severe pain in the PACU had a specific effect on this relationship. Patients among the whole population and those patients without moderate-to-severe pain in the PACU were more likely to experience postoperative 24-hour moderate-to-severe pain when they were younger than 58.5 years old, and in patients with moderate-to-severe pain in the PACU, the age threshold was 62.5 years old.

摘要

目的

探讨肺癌根治术后 24 小时内中重度疼痛与年龄的关系,以及麻醉后恢复室(PACU)中中重度疼痛对这种关系的具体影响。

设计

回顾性队列研究。

地点

单一医疗中心。

参与者

2018 年至 2020 年期间行肺癌根治术且年龄≥18 岁的患者。

测量指标

术后 24 小时内中重度疼痛。

结果

共纳入 3764 例患者进行分析。术后 24 小时内中重度疼痛的发生率为 28.3%。年龄对术后 24 小时内中重度疼痛的预测模型有显著影响。在全人群和 PACU 中无中重度疼痛的人群中,年龄<58.5 岁的患者术后 24 小时更容易发生中重度疼痛,而在 PACU 中有中重度疼痛的患者,年龄阈值为 62.5 岁。

结论

对于行择期肺癌根治术的患者,年龄与术后 24 小时内中重度疼痛相关,PACU 中的中重度疼痛对这种关系有特定影响。全人群和 PACU 中无中重度疼痛的患者年龄<58.5 岁时更容易发生术后 24 小时内中重度疼痛,而 PACU 中有中重度疼痛的患者,年龄阈值为 62.5 岁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e81f/11331832/b5d2b8f09b63/bmjopen-14-8-g001.jpg

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