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水痘肺炎合并深静脉血栓形成和肺栓塞作为男性罕见表现:病例报告

Varicella Pneumonia with Deep Venous Thrombosis and Pulmonary Embolism as Rare Presentations for Male: Case Report.

作者信息

Dallah Mohammad, Hmaideh Ahmad, Hashoom Yaser, Kaesom Ammaar, Gazhal Nusima

机构信息

Department of Pulmonology, Syrian Board of Medical Specialties, Idlib, Syria.

Department of Internal Medicine, Syrian Board of Medical Specialties, Idlib, Syria.

出版信息

Avicenna J Med. 2025 Apr 2;15(1):46-49. doi: 10.1055/s-0045-1802594. eCollection 2025 Jan.

Abstract

This case report presents the case of a middle-aged man who experienced a rare and severe presentation of varicella infection, with the development of varicella pneumonia and the rare complications of deep venous thrombosis, and a subsequent pulmonary embolism. Despite being immunocompetent, the patient's varicella infection resulted in an atypical and complex clinical course. The individual initially presented with a vesicopustular rash, fever, and fatigue, which progressed to severe hypoxia and dyspnea. Radiological findings revealed diffuse bilateral nodular consolidation consistent with varicella pneumonia. Although varicella pneumonia is well documented, its occurrence in immunocompetent individuals is uncommon. In the context of varicella infection, it is very rare, particularly in the absence of immunodeficiency and with no other risk factors, in a male patient. This case underscores the importance of maintaining a high index of clinical suspicion to promptly diagnose and treat potentially life-threatening complications associated with varicella infection in otherwise healthy individuals. Key learning points include the necessity of early recognition and intervention to mitigate severe complications and the potential need for thromboprophylaxis in varicella pneumonia patients and suggests the potential need for thromboprophylaxis in patients with varicella pneumonia to prevent thrombotic events.

摘要

本病例报告介绍了一名中年男性患者,该患者经历了水痘感染罕见且严重的表现,并发水痘肺炎以及深静脉血栓形成和随后的肺栓塞等罕见并发症。尽管患者免疫功能正常,但其水痘感染却导致了非典型且复杂的临床病程。该患者最初表现为脓疱性皮疹、发热和疲劳,随后发展为严重缺氧和呼吸困难。影像学检查结果显示双侧弥漫性结节状实变,符合水痘肺炎表现。虽然水痘肺炎已有充分记载,但其在免疫功能正常个体中发生并不常见。在水痘感染的情况下,尤其是在没有免疫缺陷且无其他危险因素的男性患者中,这种情况极为罕见。该病例强调了在看似健康的个体中保持高度临床怀疑以及时诊断和治疗与水痘感染相关的潜在危及生命并发症的重要性。关键要点包括早期识别和干预以减轻严重并发症的必要性,以及水痘肺炎患者可能需要进行血栓预防,并提示水痘肺炎患者预防血栓形成事件可能需要进行血栓预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5b/12088795/fdfc5cf99aea/10-1055-s-0045-1802594-i240005-1.jpg

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