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主动脉瓣钙化:关于其在主动脉瓣狭窄评估中的作用以及作为经导管主动脉瓣植入术后结果预测指标的叙述性综述

Aortic Valve Calcium: A Narrative Review of its Role in the Assessment of Aortic Stenosis and as a Predictor of Post-transcatheter Aortic Valve Implantation Outcomes.

作者信息

Krzowski James, Weir-McCall Jonathan, D'Errico Luigia, Costopoulos Charis, Costanzo Pierluigi

机构信息

Royal Papworth Hospital, Royal Papworth Hospital NHS Foundation Trust Cambridge, UK.

出版信息

Interv Cardiol. 2025 May 2;20:e16. doi: 10.15420/icr.2024.17. eCollection 2025.

Abstract

Degenerative aortic valve disease is the third most common cause of heart disease in the developed world. Calcific deposits accrue in the valve endothelium causing progressive stenosis of the orifice. Increasingly, transcatheter aortic valve implantation is being used in place of surgery as treatment for aortic stenosis, particularly for patients who are considered high surgical risk. Although echocardiography remains the gold standard for the diagnosis and grading of aortic valve stenosis, there is an increasing interest in the role that aortic valve calcification scoring may play in these areas. In this review, the authors evaluate the current evidence for aortic valve calcium scoring as an adjunct to echocardiography in grading, and as a prognostic marker in challenging cases. They also explore the ability of calcium scoring to predict outcomes following transcatheter aortic valve implantation.

摘要

退行性主动脉瓣疾病是发达国家中第三常见的心脏病病因。钙沉积物积聚在瓣膜内皮,导致瓣口逐渐狭窄。越来越多地,经导管主动脉瓣植入术正被用于替代手术来治疗主动脉瓣狭窄,尤其是对于那些被认为手术风险高的患者。尽管超声心动图仍然是主动脉瓣狭窄诊断和分级的金标准,但人们对主动脉瓣钙化评分在这些领域可能发挥的作用越来越感兴趣。在本综述中,作者评估了主动脉瓣钙化评分作为超声心动图分级辅助手段以及在疑难病例中作为预后标志物的现有证据。他们还探讨了钙化评分预测经导管主动脉瓣植入术后结果的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d02/12090074/0c0fcc94d419/icr-20-e16-g001.jpg

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