Munir Shauna, Connolly Michael, Davies Andrew Neil
Our Lady's Hospice & Care Services (Community Palliative Care), Dublin, Ireland.
University College Dublin School of Nursing, Midwifery and Health Systems, Dublin, Ireland.
Support Care Cancer. 2025 May 21;33(6):486. doi: 10.1007/s00520-025-09550-2.
Sleep disturbances are a common yet overlooked symptom in patients with advanced cancer. Pharmacological interventions have been widely used to manage sleep disturbances; however, concerns related to their adverse effects have resulted in a need for alternative interventions. The purpose of this scoping review is to appraise the published literature on the non-pharmacological management of sleep disturbances in patients with advanced cancer.
This scoping review was completed using the recommended methodological framework. An extensive literature search was completed using five electronic databases (Medline, CINAHL, Embase, APA PsycINFO, CENTRAL) and the Cochrane library. There were no restrictions applied to the search in relation to the years published. Only studies published in the English language were included.
We identified 9 studies published between 2010 and 2023 which focused on non-pharmacological management of sleep disturbances in patients with advanced cancer. Specific interventions included cognitive behavioural therapy, mindfulness-based therapies, bright light therapy, sleep hygiene, and other non-standard interventions. Improvements in sleep disturbance were noted in all studies, but only some studies showed statistical significance.
This scoping review identified a relatively small number of relevant studies, involving a relatively small number of participants. Moreover, the studies involved very different interventions, with very different methodologies (including type/time of assessments). Thus, it is difficult to recommend any particular non-pharmacological intervention at this time. Nevertheless, non-pharmacological interventions undoubtedly have a role to play in the management of sleep disturbance in patients with advanced cancer.
睡眠障碍是晚期癌症患者常见但被忽视的症状。药物干预已被广泛用于管理睡眠障碍；然而，对其不良反应的担忧导致需要替代干预措施。本范围综述的目的是评估已发表的关于晚期癌症患者睡眠障碍非药物管理的文献。
本范围综述采用推荐的方法框架完成。使用五个电子数据库（Medline、CINAHL、Embase、APA PsycINFO、CENTRAL）和Cochrane图书馆完成了广泛的文献检索。对发表年份的检索没有限制。仅纳入以英文发表的研究。
我们确定了2010年至2023年间发表的9项研究，这些研究专注于晚期癌症患者睡眠障碍的非药物管理。具体干预措施包括认知行为疗法、正念疗法、强光疗法、睡眠卫生和其他非标准干预措施。所有研究均指出睡眠障碍有所改善，但只有部分研究显示出统计学意义。
本范围综述确定的相关研究数量相对较少，涉及的参与者数量也相对较少。此外，这些研究涉及非常不同的干预措施，采用了非常不同的方法（包括评估类型/时间）。因此，目前很难推荐任何特定的非药物干预措施。尽管如此，非药物干预措施无疑在晚期癌症患者睡眠障碍的管理中具有一定作用。
