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荷兰版国王帕金森病疼痛量表的验证

Validation of the Dutch version of the King's Parkinson's disease pain scale.

作者信息

Alkaduhimi Nour, Kerst Yvonne, Vlaar Annemarie, Berendse Henk, Weinstein Henry, Scherder Erik

机构信息

Department of Clinical Neuropsychology, VU-university, van der Boechorstraat 1, Amsterdam, 1081 BT, The Netherlands.

Department of Clinical Neuropsychology, Wijnand Nuijenstraat 18, Amsterdam, 1061 TX, The Netherlands.

出版信息

BMC Neurol. 2025 May 21;25(1):214. doi: 10.1186/s12883-025-04222-4.

Abstract

BACKGROUND

Pain in patients with Parkinson's disease (PD)is often underdiagnosed and, therefore, undertreated. The King's Parkinson's Pain Scale (KPPS) is one of the few validated tools specifically designed to assess pain in patients with Parkinson's disease but lacks a Dutch version. This study aims to validate the KPPS for patients in the Netherlands and to examine which cognitive functions are related to the comprehension of the KPPS.

METHODS

The KPPS was translated into Dutch and validated in 70 patients with PD through internal consistency, convergent and discriminant validity testing. Patients had been diagnosed with PD for an average of 5.65 years. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA).

RESULTS

The Dutch KPPS showed acceptable reliability (Cronbach's alpha = 0.69), though its factor structure differed from the original. Convergent validity was confirmed via significant correlations with the Numerical Rating Scale (NRS), while discriminant validity was supported through correlations with the Non-Motor Symptoms Scale (NMSS) and EQ-5D-3 L. Verbal memory and abstract thinking showed a tendency toward significance in their association with pain scores.

CONCLUSION

The Dutch KPPS is a reliable and valid tool for assessing pain in Dutch patients with PD, though its structure differs from the original. These differences may reflect variability in pain perception or classification, highlighting the need for further research integrating the PD-PCS framework to refine pain assessment in PD.

摘要

背景

帕金森病(PD)患者的疼痛常常未得到充分诊断,因此治疗不足。国王帕金森疼痛量表(KPPS)是专门为评估帕金森病患者疼痛而设计的少数经过验证的工具之一,但缺乏荷兰语版本。本研究旨在验证荷兰版的KPPS,并研究哪些认知功能与对KPPS的理解有关。

方法

将KPPS翻译成荷兰语,并通过内部一致性、收敛效度和区分效度测试在70例PD患者中进行验证。患者被诊断为PD的平均时间为5.65年。使用蒙特利尔认知评估量表(MoCA)评估认知功能。

结果

荷兰版KPPS显示出可接受的信度(克朗巴哈系数α=0.69),但其因子结构与原版不同。通过与数字评定量表(NRS)的显著相关性证实了收敛效度,而通过与非运动症状量表(NMSS)和EQ-5D-3L的相关性支持了区分效度。言语记忆和抽象思维与疼痛评分的关联显示出显著趋势。

结论

荷兰版KPPS是评估荷兰PD患者疼痛的可靠有效工具,尽管其结构与原版不同。这些差异可能反映了疼痛感知或分类的变异性,突出了进一步整合PD-PCS框架以完善PD疼痛评估的研究需求。

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Minimal clinically important difference of the King's Parkinson's disease Pain Scale.帕金森病疼痛量表的最小临床重要差异。
Disabil Rehabil. 2023 May;45(10):1680-1683. doi: 10.1080/09638288.2022.2074152. Epub 2022 May 12.
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Dopamine in Parkinson's disease.帕金森病中的多巴胺。
Clin Chim Acta. 2021 Nov;522:114-126. doi: 10.1016/j.cca.2021.08.009. Epub 2021 Aug 11.

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