Alkhaldi Abdullah, Althwanay Reem, Alsalamah Abdullah Saad, Aldakheel Abdulelah Mashhor, Awad Baraa, Halawani Mohammed
Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, King Abdul-Aziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Am J Case Rep. 2025 May 22;26:e946474. doi: 10.12659/AJCR.946474.
BACKGROUND Pilomatrixomas are benign skin tumors that tend to occur in children. They most commonly arise in the head and neck region, but their appearance in the ear, especially the earlobe, is rare. Clinically, these lesions present as firm, non-tender nodules, occasionally with a reddish or bluish tint. Given the lesions' typical features, experienced clinicians may opt for surgical excision without extensive workup. Still, diagnosis can be challenging when the lesion is located in an unusual site, like the auricle, where it can resemble other skin conditions. In this report, we describe a case of earlobe pilomatrixoma and outline its clinical presentation, surgical management, and histopathological findings. CASE REPORT A 6-year-old girl presented with a painless, stable mass on her right earlobe, first noticed at the age of 3 years. Physical examination revealed a firm, non-tender, well-circumscribed, mobile lesion, with no overlying skin changes or history of trauma. No previous imaging or investigations were conducted. After discussion, surgical excision was performed. Histopathological analysis showed alternating eosinophilic and basophilic calcified areas, abundant anucleate eosinophilic ghost cells, and multinucleated giant cells, confirming pilomatrixoma. Notably, basaloid and transitional cells were absent, suggesting lesion maturity. CONCLUSIONS This case emphasizes the importance of considering pilomatrixoma in the differential diagnosis of pediatric head and neck masses and how it might even present in some unusual locations, such as the auricle. Recognizing its clinical features can facilitate effective management while minimizing unnecessary diagnostic tests. In this case, we highlighted an efficient approach and raised awareness of pilomatrixoma's distinctive presentation.
背景 毛发上皮瘤是一种常见于儿童的良性皮肤肿瘤。它们最常发生于头颈部区域,但在耳部尤其是耳垂出现的情况较为罕见。临床上,这些病变表现为质地坚硬、无压痛的结节,偶尔带有红色或蓝色色调。鉴于病变的典型特征,经验丰富的临床医生可能会选择在没有进行广泛检查的情况下进行手术切除。然而,当病变位于不寻常的部位,如耳廓时,诊断可能具有挑战性,因为它可能类似于其他皮肤疾病。在本报告中,我们描述了一例耳垂毛发上皮瘤病例,并概述了其临床表现、手术治疗及组织病理学发现。病例报告 一名6岁女孩右耳垂出现一个无痛、大小稳定的肿块,3岁时首次发现。体格检查发现一个质地坚硬、无压痛、边界清晰、可活动的病变,其上覆皮肤无变化,也无外伤史。此前未进行过影像学检查或其他调查。经讨论后进行了手术切除。组织病理学分析显示有嗜酸性和嗜碱性钙化区域交替出现、大量无核嗜酸性影细胞以及多核巨细胞,确诊为毛发上皮瘤。值得注意的是,未见基底样细胞和过渡细胞,提示病变成熟。结论 本病例强调了在小儿头颈部肿块的鉴别诊断中考虑毛发上皮瘤的重要性,以及它甚至可能出现在一些不寻常的部位,如耳廓。认识其临床特征有助于进行有效的管理,同时尽量减少不必要的诊断检查。在本病例中,我们突出了一种有效的方法,并提高了对毛发上皮瘤独特表现的认识。