Rombel N, Lim C, Majeed A, Abdul-Jabbar S, McClelland G R, Jones S A
Institute of Pharmaceutical Science, School of Cancer and Pharmaceutical Sciences, King's College London London UK
Centre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, School of Cancer and Pharmaceutical Sciences, King's College London London UK.
RSC Pharm. 2025 May 5. doi: 10.1039/d5pm00003c.
Supplying vitamin D supplements to all older adults is beneficial and cost-effective. However, operationalising this supply to residents in long-term care is problematic. This study aimed to understand the challenges of vitamin D supplement provision by auditing the extent of supplementation, measuring the quality of the supplements and investigating the attitudes towards supplement provision in UK care homes. This case study investigated the supply of vitamin D supplement formulations in four UK care homes and analysed the vitamin D content of nine formulation types. It employed semi-structured interviews with care home stakeholders to understand attitudes toward vitamin D supply. Across the nine analysed products, there was >50% variability in their quality (75-137% of the label), but 44% of supplements were of medicinal grade. One tablet from a food-grade product contained 167% vitamin D, and one medicinal-grade tablet only contained 70% vitamin D. Interviews with care home staff highlighted four challenges to providing supplements: the perceived responsibility of healthcare professionals to supplement, difficulties obtaining prescription medications, the absence of national/local strategies, and the financial burden. This study demonstrated sub-optimal vitamin D supplement supply to care home residents, with staff unclear about who was responsible for choosing the correct type of vitamin D supplement, who paid for it, and who was to supply it. This study suggests a new approach to delivering vitamin D supplements to older adults is needed.
给所有老年人补充维生素D是有益且具有成本效益的。然而,向长期护理机构的居民提供这种补充剂存在问题。本研究旨在通过审核补充情况、测量补充剂质量以及调查英国养老院对补充剂供应的态度,来了解维生素D补充剂供应面临的挑战。本案例研究调查了英国四家养老院维生素D补充剂配方的供应情况,并分析了九种配方类型的维生素D含量。研究采用半结构化访谈,与养老院利益相关者进行交流,以了解他们对维生素D供应的态度。在所分析的九种产品中,其质量存在超过50%的差异(为标签标注量的75 - 137%),但44%的补充剂为药用级。一种食品级产品的一片药片中维生素D含量为167%,而一片药用级药片中维生素D含量仅为70%。对养老院工作人员的访谈突出了提供补充剂面临的四个挑战:医疗保健专业人员对补充剂供应的认知责任、获取处方药的困难、缺乏国家/地方策略以及经济负担。本研究表明,养老院居民的维生素D补充剂供应情况欠佳,工作人员不清楚谁负责选择正确类型的维生素D补充剂、谁来支付费用以及谁来提供。本研究表明,需要一种向老年人提供维生素D补充剂的新方法。