Yu Yi, Teng Lirong, Liu Juntao, Liu Xinyan, Peng Ping, Zhou Qian, Liu Congcong
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
National Clinical Research Center for Obstetric and Gynecologic Diseases, Beijing 100730, China.
Matern Fetal Med. 2022 Sep 14;6(1):50-53. doi: 10.1097/FM9.0000000000000168. eCollection 2024 Jan.
Pregnancy with solid pseudopapillary tumor of the pancreas (SPTP) is rare. Because pregnancy hormones may cause tumor progression, the management and treatment of SPTP need to balance the safety of pregnant women and fetuses with surgical treatment. We reported a case of a giant pancreatic tumor diagnosed during pregnancy that was considered to be SPTP. Examinations also showed hepatitis B virus infection and severe decompensation of liver cirrhosis. Medical termination of pregnancy was performed. The patient has lived with the tumor until now without surgery. We retrieved the published case reports, summarized the clinical characteristics of pregnancy with SPTP, and explored its management during the perinatal period. Most patients with SPTP have a good prognosis with good maternal and fetal outcomes, and it is important to choose an appropriate treatment method and timing. However, pregnancy combined with decompensated liver cirrhosis needs to be terminated in a timely manner because of its high-risk status.
胰腺实性假乳头状瘤（SPTP）合并妊娠较为罕见。由于妊娠激素可能导致肿瘤进展，SPTP的管理和治疗需要在孕妇及胎儿安全与手术治疗之间取得平衡。我们报告了1例在孕期诊断为巨大胰腺肿瘤且考虑为SPTP的病例。检查还显示该患者感染乙肝病毒且肝硬化严重失代偿。遂进行了药物引产。该患者至今未接受手术，一直带瘤生存。我们检索了已发表的病例报告，总结了SPTP合并妊娠的临床特征，并探讨了其围产期管理。大多数SPTP患者预后良好，母婴结局良好，选择合适的治疗方法和时机很重要。然而，妊娠合并失代偿期肝硬化因其高危状态需要及时终止妊娠。
