de Alegria Samantha Gomes, da Silva Matheus Mello, Oliveira Jéssica Gabriela Messias, de Azevedo Beatriz Luiza Pinheiro Alves, Saraiva Nathália Alves de Oliveira, Ferreira Isabelle da Nóbrega, Silva Joana Acar, Mafort Thiago Thomaz, da Costa Cláudia Henrique, Lopes Agnaldo José
Post-Graduation Programme in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2º andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil.
Rehabilitation Sciences Post-Graduation Programme, Centro Universitário Augusto Motta (UNISUAM), Rua Dona Isabel, 94, Bonsucesso, Rio de Janeiro 21032-060, Brazil.
Adv Respir Med. 2025 May 20;93(3):9. doi: 10.3390/arm93030009.
There is limited research on the impact of a physiotherapy-guided rehabilitation program (PGRP) on lung structure in systemic sclerosis (SSc). Lung ultrasound (LUS) has been used for over a decade to identify interstitial lung disease associated with SSc (SSc-ILD). This study aims to evaluate the impact of a PGRP on LUS signals in women with SSc-ILD and women without ILD (SSc-wILD). This is a longitudinal quasi-experimental study that included 33 women with SSc. The results show that changes in LUS were observed in 22 participants, especially B-lines > two. Before the PGRP the median of B-lines > two was three (0-7), while after the PGRP it was three (0-6) ( = 0.020). The aeration score was eight (0-16.5) pre-PGRP and three (0-16) post-PGRP ( = 0.013). Analyzing the impact of the PGRP on LUS signals in SSc-ILD and SSc-wILD groups, the main change observed was a reduction in B-lines > two between pre-PGRP and post-PGRP in the SSc-ILD group ( = 0.0004). The SSc-ILD group had a higher aeration score than the SSc-wILD group both pre-PGRP ( < 0.0001) and post-PGRP ( = 0.0001)]. In conclusion, LUS may be a complementary tool for assessing pre- and post-PGRP changes in people with SSc-ILD and SSc-wILD. Our data also suggest that the PGRP can elicit measurable changes in LUS findings in SSc, particularly in SSc-ILD. These findings support the inclusion of LUS in the routine monitoring of SSc and the use of a PGRP as a non-pharmacologic adjunctive strategy in SSc.
关于物理治疗指导的康复计划（PGRP）对系统性硬化症（SSc）肺部结构影响的研究有限。肺超声（LUS）已被用于识别与SSc相关的间质性肺病（SSc-ILD）超过十年。本研究旨在评估PGRP对患有SSc-ILD的女性和未患ILD的女性（SSc-wILD）的LUS信号的影响。这是一项纵向准实验研究，纳入了33名患有SSc的女性。结果显示，22名参与者的LUS出现了变化，尤其是B线>两条。在PGRP之前，B线>两条的中位数为3（0-7），而在PGRP之后为3（0-6）（P = 0.020）。通气评分在PGRP前为8（0-16.5），PGRP后为3（0-16）（P = 0.013）。分析PGRP对SSc-ILD组和SSc-wILD组LUS信号的影响，观察到的主要变化是SSc-ILD组在PGRP前和PGRP后B线>两条的数量减少（P = 0.0004）。SSc-ILD组在PGRP前（P < 0.0001）和PGRP后（P = 0.0001）的通气评分均高于SSc-wILD组。总之，LUS可能是评估SSc-ILD和SSc-wILD患者PGRP前后变化的辅助工具。我们的数据还表明，PGRP可以在SSc患者中引起LUS检查结果的可测量变化，特别是在SSc-ILD患者中。这些发现支持将LUS纳入SSc的常规监测，并将PGRP用作SSc的非药物辅助策略。
