Zheng Shuang, Yu Yang, Liang Siquan, Hou Weijia, Hu Xinru, Wu Fan, Li Haitao, Wu Jingchao, Wang Qi, Wu Jialing
Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, 300070, China.
Department of Rehabilitation, Tianjin Huanhu Hospital, Tianjin, 300350, China.
Neurol Sci. 2025 May 23. doi: 10.1007/s10072-025-08222-7.
The postoperative motor function of patients with Parkinson's disease (PD) treated with deep brain stimulation (DBS) is significantly improved, but the level of physical activity is still low. Tele-rehabilitation provides a convenient and flexible rehabilitation method. The aim of this study was to explore the effects of tele-rehabilitation after DBS on cardiopulmonary fitness and gait in PD patients.
To explore the effects of early post-DBS tele-rehabilitation on cardiopulmonary fitness and gait in PD patients.
There were 24 patients and classified them into two groups, i.e., Group A (postoperative tele-rehabilitation, n = 14) and Group B (only surgical treatment, n = 10). Movement Disorder Society-unified Parkinson's disease rating scale III(MDS-UPDRSIII), the six-minute walking test (6MWT), pulmonary function test and Timed Up and Go (TUG) test were used as primary outcome variables, while the Tinetti performance-oriented mobility assessment (POMA), the Borg scale at the end of the 6MWT and 39-item Parkinson's disease questionnaire (PDQ-39) were used as secondary outcome variables.
The 6MWT, Tinetti score, FVC and FEV1 in Group A were significantly higher than those in Group B (P < 0.05), and Borg scale score at the end of 6MWT and TUG were significantly lower than those in Group B (P < 0.05). Compared with baseline, MDS-UPDRS III score, the 6MWT, TUG, Tinetti score, FVC, FEV1, Borg scale score at the end of 6MWT and PDQ-39 were significantly improved in Group A (P < 0.05). MDS-UPDRS III score and Tinetti score were significantly improved in Group B at follow-up (P < 0.05).
Tele-rehabilitation after DBS can improve cardiopulmonary fitness and the functional walking ability of PD patients.
接受脑深部电刺激（DBS）治疗的帕金森病（PD）患者术后运动功能显著改善，但身体活动水平仍然较低。远程康复提供了一种方便灵活的康复方法。本研究旨在探讨DBS术后远程康复对PD患者心肺适能和步态的影响。
探讨DBS术后早期远程康复对PD患者心肺适能和步态的影响。
选取24例患者，分为两组，即A组（术后远程康复，n = 14）和B组（仅手术治疗，n = 10）。采用运动障碍协会统一帕金森病评定量表III（MDS-UPDRSIII）、六分钟步行试验（6MWT）、肺功能测试和计时起立行走（TUG）测试作为主要结局变量，同时采用Tinetti以性能为导向的移动性评估（POMA）、6MWT结束时的Borg量表和39项帕金森病问卷（PDQ-39）作为次要结局变量。
A组的6MWT、Tinetti评分、FVC和FEV1显著高于B组（P < 0.05），6MWT结束时的Borg量表评分和TUG显著低于B组（P < 0.05）。与基线相比，A组的MDS-UPDRS III评分、6MWT、TUG、Tinetti评分、FVC、FEV1、6MWT结束时的Borg量表评分和PDQ-39显著改善（P < 0.05）。随访时B组的MDS-UPDRS III评分和Tinetti评分显著改善（P < 0.05）。
DBS术后远程康复可改善PD患者的心肺适能和功能性步行能力。
