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英国多民族人群孕期体重增加的决定因素:来自布拉德福德出生队列研究的结果。

Determinants of gestational weight gain during pregnancy in a multiethnic UK-based population: Findings from the Born in Bradford cohort study.

作者信息

Araújo Petra A T, Quigley Maria A, Santorelli Gillian, Coathup Victoria

机构信息

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, Oxfordshire, United Kingdom.

Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, United Kingdom.

出版信息

PLoS One. 2025 May 23;20(5):e0323278. doi: 10.1371/journal.pone.0323278. eCollection 2025.

Abstract

INTRODUCTION

Unhealthy maternal weight gain during pregnancy is associated with deleterious outcomes to mothers and their offspring. Current literature on the determinants of gestational weight gain yields inconsistent results, with limited research conducted in the United Kingdom. This study investigates potential determinants of unhealthy gestational weight gain in a multiethnic cohort within Bradford, United Kingdom.

METHODS

The study analysed 7,769 singleton pregnancies from the Born in Bradford Cohort. Women were enrolled at ~26 weeks' gestation. Weight at first antenatal appointment, recruitment and/or third trimester were used to calculate weekly average weight gain. This was categorized as 'less than recommended', 'recommended' or 'more than recommended' based on the Institute of Medicine (IOM) criteria. Associations between potential determinants and gestational weight gain were assessed using multinomial logistic regression with recommended gestational weight gain as the reference.

RESULTS

Overall, 22.4% of women gained weight within the recommended range; 20.3% gained less than recommended, and 57.3% gained more than recommended. Key risk factors for gaining less weight than recommended were unhealthy baseline BMI (aOR=1.78 for underweight, aOR=1.3 for obese), higher parity (e.g. aOR=1.46 for 3 + children) and lower socioeconomic status (aOR=1.4). The strongest risk factors for gaining more weight than recommended were high baseline BMI (e.g. aOR=5.86 for obese) and higher psychiatric morbidity score (aOR=1.22); being underweight (aOR=0.58) and higher parity (e.g. aOR=0.70 for 3 + children) were associated with a lower risk of gaining more weight than recommended. The effect of mental health seemed to be particularly important among women of Pakistani background, while parity seemed to play a major role among White British women.

CONCLUSION

Baseline BMI, age, socioeconomic position, parity and mental health are associated with unhealthy weight gain during pregnancy in a multiethnic UK population. These findings can help identify at-risk women and inform targeted preventative strategies.

摘要

引言

孕期母亲体重增加不健康与母亲及其后代的不良后果相关。目前关于孕期体重增加决定因素的文献结果不一致,在英国进行的研究有限。本研究调查了英国布拉德福德一个多民族队列中孕期体重增加不健康的潜在决定因素。

方法

该研究分析了来自布拉德福德出生队列的7769例单胎妊娠。女性在妊娠约26周时入组。首次产前检查、招募时和/或孕晚期的体重用于计算每周平均体重增加。根据医学研究所(IOM)标准,将其分为“低于推荐值”、“推荐值”或“高于推荐值”。使用多项逻辑回归评估潜在决定因素与孕期体重增加之间的关联,以推荐的孕期体重增加为参照。

结果

总体而言,22.4%的女性体重增加在推荐范围内;20.3%的女性体重增加低于推荐值,57.3%的女性体重增加高于推荐值。体重增加低于推荐值的关键风险因素是基线BMI不健康(体重过轻的调整后比值比[aOR]=1.78,肥胖的aOR=1.3)、较高的产次(例如,有3个及以上孩子的aOR=1.46)和较低的社会经济地位(aOR=1.4)。体重增加高于推荐值的最强风险因素是高基线BMI(例如,肥胖的aOR=5.86)和较高的精神疾病发病率评分(aOR=1.22);体重过轻(aOR=0.58)和较高的产次(例如,有3个及以上孩子的aOR=0.70)与体重增加高于推荐值的风险较低相关。心理健康的影响在巴基斯坦裔背景的女性中似乎尤为重要,而产次在英国白人女性中似乎起主要作用。

结论

在英国多民族人群中,基线BMI、年龄、社会经济地位、产次和心理健康与孕期体重增加不健康相关。这些发现有助于识别高危女性,并为有针对性的预防策略提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/12101682/adc3031f7092/pone.0323278.g001.jpg

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