Popova Margarita, Gladkikh Anna, Sharova Alena, Arbuzova Tatiana, Sbarzaglia Valeriya, Klyuchnikova Ekaterina, Tsyganova Nadezhda, Forghani Majid, Gritseva Anastasia, Ramsay Edward, Dong Nguyen Thanh, Phu Bui Thanh, Hung Do Thai, Dedkov Vladimir
Saint Petersburg Pasteur Institute, Saint Petersburg, Russia.
Pasteur Institute in Nha Trang, Vietnam.
PLoS One. 2025 May 23;20(5):e0322924. doi: 10.1371/journal.pone.0322924. eCollection 2025.
Mosquitoes are important vectors for various infectious pathogens. More than 200 species of mosquitoes are common in Vietnam, one of the main carriers of viruses that are important for humans is the mosquito of the genus Aedes aegypti. Metavirome sequencing can shed light on the diversity of mosquito-borne viruses classified as insect-specific viruses (ISV). After BLAST analysis using the viral database, contigs were classified as belonging to seventeen ISVs. Ten of them are distributed among five families: Totiviridae; Flaviviridae; Partitiviridae; Phenuiviridae; and Orthomyxoviridae. The other seven species belonged to recently identified RNA viruses whose taxonomic position is undefined in the current classification of the International Committee on Taxonomy of Viruses (ICTV). This is the first study to reveal the diversity of RNA viruses associated with Aedes aegypti mosquitoes in Vietnam, while highlighting the need for further study of ISV in mosquito vectors.
蚊子是多种传染性病原体的重要传播媒介。越南有200多种常见蚊子，对人类重要的病毒的主要携带者之一是埃及伊蚊。宏病毒组测序可以揭示被归类为昆虫特异性病毒（ISV）的蚊媒病毒的多样性。使用病毒数据库进行BLAST分析后，重叠群被归类为属于17种ISV。其中10种分布在五个科中：双链RNA病毒科；黄病毒科；分体病毒科；白蛉病毒科；和正粘病毒科。其他七种属于最近鉴定出的RNA病毒，其分类地位在国际病毒分类委员会（ICTV）的当前分类中尚未确定。这是第一项揭示越南埃及伊蚊相关RNA病毒多样性的研究，同时强调了对蚊媒中ISV进行进一步研究的必要性。
