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哺乳会降低大鼠正中隆起内侧和外侧的多巴胺周转率。

Suckling decreases dopamine turnover in both medial and lateral aspects of the median eminence in the rat.

作者信息

Selmanoff M, Gregerson K A

出版信息

Neurosci Lett. 1985 Jun 4;57(1):25-30. doi: 10.1016/0304-3940(85)90035-7.

DOI:10.1016/0304-3940(85)90035-7
PMID:4041019
Abstract

The effect of suckling on dopamine (DA) turnover was studied in the medial and lateral aspects of the median eminence. In 10-day postpartum lactating rats suckling decreased DA turnover 2.2-fold in the medial and 2.1-fold in the lateral median eminence. Norepinephrine turnover did not differ in suckled and non-suckled rats. These results are consistent with the hypothesis that decreased DA release is a component of the neuroendocrine reflex mediating suckling-induced prolactin release. The results further indicate that dopaminergic neurons distributing to both medial and lateral aspects of the median eminence are involved in the suckling response.

摘要

研究了哺乳对正中隆起内侧和外侧多巴胺(DA)代谢的影响。在产后10天的泌乳大鼠中,哺乳使正中隆起内侧的DA代谢降低了2.2倍,外侧降低了2.1倍。哺乳大鼠和未哺乳大鼠的去甲肾上腺素代谢没有差异。这些结果与以下假设一致,即DA释放减少是介导哺乳诱导催乳素释放的神经内分泌反射的一个组成部分。结果还表明,分布于正中隆起内侧和外侧的多巴胺能神经元都参与了哺乳反应。

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Suckling decreases dopamine turnover in both medial and lateral aspects of the median eminence in the rat.哺乳会降低大鼠正中隆起内侧和外侧的多巴胺周转率。
Neurosci Lett. 1985 Jun 4;57(1):25-30. doi: 10.1016/0304-3940(85)90035-7.
2
Decreased dopamine turnover in the median eminence in response to suckling in the lactating rat.泌乳大鼠在哺乳时,正中隆起处多巴胺更新率降低。
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The lateral and medial median eminence: distribution of dopamine, norepinephrine, and luteinizing hormone-releasing hormone and the effect of prolactin on catecholamine turnover.外侧和内侧正中隆起:多巴胺、去甲肾上腺素和促黄体生成激素释放激素的分布以及催乳素对儿茶酚胺代谢的影响。
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Effects of suckling on serum prolactin levels and catecholamine concentrations and turnover in discrete brain regions.哺乳对血清催乳素水平、儿茶酚胺浓度以及离散脑区中儿茶酚胺周转率的影响。
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