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绝经前后女性心血管代谢风险的测定

Determination of cardiometabolic risk in pre- and post-menopausal women.

作者信息

Orhan İlksen, Koçak Hatice Serap, Kaplan Emine

机构信息

Department of Nursing, Faculty of Health Sciences, Munzur University, Tunceli, Turkey.

Faculty of Health Sciences, Public Health Nursing Department, Gaziantep University, Gaziantep, Turkey.

出版信息

BMC Cardiovasc Disord. 2025 May 24;25(1):399. doi: 10.1186/s12872-025-04850-1.

Abstract

OBJECTIVE

The study was designed to determine and compare the cardiometabolic risk in premenopausal and postmenopausal women.

METHODS

Data were collected using cross-sectional and correlational study. In this study, the sociodemographic characteristics, anthropometric measurements, and biochemical parameters of menopausal women were examined.

RESULTS

The average age of menopausal women is higher compared to premenopausal women. Menopausal duration, number of children, daily cigarette consumption, body weight, body mass index (BMI), waist circumference, hip circumference, waist-to-hip ratio, systolic and diastolic blood pressure, fasting blood glucose, hemoglobin, AST (aspartate aminotransferase), and Framingham risk score are higher in menopausal women compared to premenopausal women. Conversely, height, HDL (high-density lipoprotein) level, LDL (low-density lipoprotein) level, TSH (thyroid-stimulating hormone), ALT (alanine aminotransferase), HbA1c (glycated hemoglobin), serum albumin, and visceral adiposity index (VAI) values are lower in menopausal women compared to premenopausal women.

CONCLUSION

These findings indicate changes in the metabolic profiles of menopausal women. This study could serve as an important resource for assessing the health status of menopausal women and for implementing appropriate measures.

CLINICAL TRIAL NUMBER

not applicable.

摘要

目的

本研究旨在确定并比较绝经前和绝经后女性的心脏代谢风险。

方法

采用横断面和相关性研究收集数据。在本研究中,对绝经女性的社会人口学特征、人体测量指标和生化参数进行了检查。

结果

绝经女性的平均年龄高于绝经前女性。与绝经前女性相比,绝经女性的绝经持续时间、子女数量、每日吸烟量、体重、体重指数(BMI)、腰围、臀围、腰臀比、收缩压和舒张压、空腹血糖、血红蛋白、谷草转氨酶(AST)和弗雷明汉风险评分更高。相反,与绝经前女性相比,绝经女性的身高、高密度脂蛋白(HDL)水平、低密度脂蛋白(LDL)水平、促甲状腺激素(TSH)、谷丙转氨酶(ALT)、糖化血红蛋白(HbA1c)、血清白蛋白和内脏脂肪指数(VAI)值更低。

结论

这些发现表明绝经女性的代谢谱发生了变化。本研究可为评估绝经女性的健康状况和采取适当措施提供重要参考。

临床试验编号

不适用。

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Women's experience of menopause: a systematic review of qualitative evidence.女性更年期经历:定性证据的系统评价
JBI Database System Rev Implement Rep. 2015 Sep 16;13(8):250-337. doi: 10.11124/jbisrir-2015-1948.

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