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一项关于采用脂肪量指数标准评估社区老年女性肌少症肥胖的提议。

A proposal for a fat mass index criterion for the assessment of sarcopenic obesity in the community-dwelling older women.

作者信息

Pérez-Ros Pilar, Flor-Rufino Cristina, Fonfría-Vivas Rosa, Pablos-Monzó Ana, Barrahina-Igual Joaquin, Martínez-Arnau Francisco Miguel

机构信息

Department of Nursing, Universitat de València, Menendez Pelayo 19, 46010, Valencia, Spain.

Department of Physiotherapy, Universitat de Valencia, Gascó Oliag 5, 46010, Valencia, Spain.

出版信息

Clin Nutr ESPEN. 2025 Aug;68:451-456. doi: 10.1016/j.clnesp.2025.05.033. Epub 2025 May 23.

Abstract

INTRODUCTION

Among older populations, sarcopenic obesity (SO) is a prevalent condition, characterized by the coexistence of both low muscle mass and excess fat. Accurate early diagnosis is crucial for managing this disorder and preventing its associated health risks. The aim of this study is to provide a fat mass index (FMI) cutoff value for diagnosing SO in community-dwelling older women according to (Blinded) consensus.

MATERIAL AND METHODS

This cross-sectional study included a sample of older women aged 70 years and older, residing in community settings in (blinded).

RESULTS

Among the 145 included women (mean age 77.4 years), prevalence of SO was 16.6 %. A complete assessment revealed independence and adequate nutritional status, despite high levels of comorbidity. Significant between-group differences were observed in body mass index (BMI), fat mass, and brachial and waist circumferences, but not in calf circumference. Compared to women without SO, those with the condition had lower handgrip strength but performed similarly in the sit-to-stand test. Mean FMI was higher in the SO group. A ROC curve identified an FMI cutoff of >12 kg/m, with 77 % sensitivity and 75 % specificity, and a post-test probability of SO of 39.2 %.

CONCLUSIONS

Our results indicate that FMI is a promising diagnostic tool for SO, with acceptable sensitivity and specificity values for clinical implementation. However, further research is needed to validate these findings across different populations and healthcare settings to ensure its broader applicability.

摘要

引言

在老年人群中,肌少性肥胖(SO)是一种普遍存在的状况,其特征是肌肉量低和脂肪过多并存。准确的早期诊断对于管理这种疾病和预防其相关健康风险至关重要。本研究的目的是根据(盲法)共识提供一个脂肪量指数(FMI)临界值,用于诊断社区居住的老年女性中的SO。

材料与方法

这项横断面研究纳入了居住在(盲法)社区环境中的70岁及以上老年女性样本。

结果

在纳入的145名女性(平均年龄77.4岁)中,SO的患病率为16.6%。尽管合并症水平较高,但全面评估显示她们具有独立性且营养状况良好。在体重指数(BMI)、脂肪量、肱围和腰围方面观察到组间存在显著差异,但小腿围无差异。与无SO的女性相比,患有SO的女性握力较低,但在坐立试验中的表现相似。SO组的平均FMI较高。ROC曲线确定FMI临界值>12 kg/m²,敏感性为77%,特异性为75%,SO的验后概率为39.2%。

结论

我们的结果表明,FMI是一种有前景的SO诊断工具,其敏感性和特异性值可接受,适用于临床应用。然而,需要进一步研究以在不同人群和医疗环境中验证这些发现,以确保其更广泛的适用性。

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