Tnimov M Kh, Semeniuk A V, Nepomniashchikh G I, Voronina N P, Shishkina L N
Biull Eksp Biol Med. 1985 Sep;100(9):365-7.
A study was made of lung and liver mononuclear phagocytes of rats exposed to severe cold (-7 degrees C). The data indicate the depression of mononuclear phagocytes under short-term (2 h) exposure to cold followed by activation of phagocytes, which was more demonstrable in the lungs. The phase modifications in the activity of mononuclear phagocytes were associated with accumulation of lipid peroxidation products (LPP) and destruction of alveolocytes. The different accumulation of LPP in the test organs of animals exposed to cold is regarded by the authors as a possible reason for functional differences of lung and liver macrophages.
对暴露于严寒（-7摄氏度）的大鼠的肺和肝单核吞噬细胞进行了一项研究。数据表明，在短期（2小时）暴露于寒冷环境下，单核吞噬细胞功能受到抑制，随后吞噬细胞被激活，这种现象在肺部更为明显。单核吞噬细胞活性的阶段性变化与脂质过氧化产物（LPP）的积累以及肺泡细胞的破坏有关。作者认为，暴露于寒冷环境的动物受试器官中LPP的不同积累可能是肺和肝巨噬细胞功能差异的一个原因。
