Awasthi Shibu S
Physiology Department, Dr. Kailash Narayan Singh (KNS) Memorial Institute of Medical Sciences, Barabanki, IND.
Cureus. 2025 Apr 24;17(4):e82921. doi: 10.7759/cureus.82921. eCollection 2025 Apr.
Stress is a common causative factor of menstrual irregularities, and the effect is supposed to be mediated by an alteration in normal pulsatile gonadotropin-releasing hormone (GnRH) secretion by stress.
A cohort of 150 apparently healthy young women as volunteers was selected randomly. They were asked to attempt the perceived stress scale-14 (PSS-14) questionnaire, and based upon their scores, 50 women were allocated into group A (score of ≤28) and group B (score of ≥29), by a stratified sampling method. Their menstrual characteristics, including age of menarche, cycle length, duration of menses, any history of heavy menstrual flow (staining/passage of clots), severe debilitating dysmenorrhea, irregularities, and pictorial blood assessment chart (PBAC) scores, were recorded. The chi-square (χ) test, Student's t-test, and Pearson's correlation coefficient were used to analyze the data using SPSS software version 21.0 (IBM Corp., Armonk, NY).
Group B had higher PBAC scores than group A (110.24±70.00 versus 87.56±38.51; t=2.007 and p=0.047). A history of menstrual irregularity was more common in group B as compared to group A (22% versus 4%; χ=7.162 and p=0.002), and a history of heavy menstrual flow was also more common in group B as compared to group A (72% versus 44%; χ=8.046 and p=0.005). In the overall selected population, PSS scores were positively correlated with a history of heavy menstrual flow (r=0.267; p=0.007) and a history of debilitating dysmenorrhea (r=0.246; p=0.014). PBAC scores were positively correlated with menstrual irregularity (r=0.497; p<0.001), the duration of menses (r=0.422; p<0.001), a history of debilitating dysmenorrhea (r=0.212; p=0.034), and a history of heavy menstrual flow (r=0.212; p=0.034). The duration of menses was positively correlated with menstrual cycle length (r=0.287; p=0.004) and a history of debilitating dysmenorrhea (r=0.211; p=0.035). The history of heavy menstrual flow was also positively correlated with the history of debilitating dysmenorrhea (r=0.323; p=0.001).
Women suffering from higher perceived stress have higher menstrual blood flow, greater blood loss, and more chances of menstrual irregularities. Perceived stress levels are positively correlated with a history of dysmenorrhea and heavy menstrual flow. Menstrual blood loss is more in women with menstrual irregularities, longer menstrual duration, a history of dysmenorrhea, and heavy menstrual flow. Longer menstrual cycles tend to have longer menstrual duration. Dysmenorrhea is positively correlated with heavier menstrual flow.
压力是月经不调的常见致病因素，其影响被认为是由压力导致正常的促性腺激素释放激素（GnRH）脉冲式分泌改变所介导的。
随机选取150名表面健康的年轻女性志愿者。她们被要求填写感知压力量表-14（PSS-14）问卷，并根据得分，采用分层抽样方法将50名女性分为A组（得分≤28）和B组（得分≥29）。记录她们的月经特征，包括初潮年龄、月经周期长度、经期持续时间、任何月经过多（染色/排出血块）、严重痛经、月经不调的病史以及图像化失血评估表（PBAC）得分。使用SPSS 21.0软件（IBM公司，纽约州阿蒙克）进行卡方（χ）检验、学生t检验和皮尔逊相关系数分析数据。
B组的PBAC得分高于A组（110.24±70.00对87.56±38.51；t = 2.007，p = 0.047）。与A组相比，B组月经不调的病史更为常见（22%对4%；χ = 7.162，p = 0.002），月经过多的病史在B组也比A组更常见（72%对44%；χ = 8.046，p = 0.005）。在整个选定人群中，PSS得分与月经过多的病史（r = 0.267；p = 0.007）和严重痛经的病史（r = 0.246；p = 0.014）呈正相关。PBAC得分与月经不调（r = 0.497；p < 0.001）、经期持续时间（r = 0.422；p < 0.001）、严重痛经的病史（r = 0.212；p = 0.034）和月经过多的病史（r = 0.212；p = 0.034）呈正相关。经期持续时间与月经周期长度（r = 0.287；p = 0.004）和严重痛经的病史（r = 0.211；p = 0.035）呈正相关。月经过多的病史也与严重痛经的病史呈正相关（r = 0.323；p = 0.001）。
感知压力较高的女性月经量更多、失血更多且月经不调的几率更高。感知压力水平与痛经病史和月经过多呈正相关。月经不调、经期较长、有痛经病史和月经过多的女性失血量更多。月经周期较长往往经期也较长。痛经与月经量较大呈正相关。
