Finell Eerika, Tolvanen Asko, Stridsman Caroline, Backman Helena, Hedman Linnéa
Faculty of Social Sciences and Business Studies, Kuopio Campus, University of Eastern Finland, Kuopio, Finland.
Methodology Centre for Human Sciences, University of Jyväskylä, Finland.
Eur Clin Respir J. 2025 May 22;12(1):2509395. doi: 10.1080/20018525.2025.2509395. eCollection 2025.
To study whether worsening asthma at school was related to generic health-related quality of life (HRQoL) and asthma-related impact and worry among 15-year-olds with current asthma in Sweden. In addition, we studied the association between worsening asthma at school at age 15 and the change in the degree to which asthma interfered with daily activities between ages 15 and 19 years.
Within the Obstructive Lung Disease in Northern Sweden (OLIN) studies, a cohort of schoolchildren has been followed from age 8 years until 19 years of age. In the current study, the sample included 266 adolescents with physician-diagnosed asthma, and either wheeze or use of asthma medication during the last 12 months at age 15 years.
At age 15, HRQoL scores were lower among those who reported worsening asthma at school (standardised beta (β) = -0.18, = 0.003), they had more asthma-related worries (β = -0.33, < 0.001) and asthma impacted their life during activities more (β = -0.46, < 0.001) than those whose asthma did not worsen. Furthermore, the more adolescents reported that asthma worsened at school at age 15, the more it was associated with the increase in the degree to which asthma interfered with their activities between 15 and 19 years (β = 0.14, = 0.038).
Worsening asthma at school was associated with lower generic health-related quality of life, higher asthma-related worry and impact on daily activities among teenagers with asthma.
研究在瑞典,学校中哮喘病情恶化是否与15岁患现患哮喘青少年的一般健康相关生活质量(HRQoL)、哮喘相关影响及担忧有关。此外,我们还研究了15岁时学校中哮喘病情恶化与15至19岁期间哮喘对日常活动干扰程度变化之间的关联。
在瑞典北部阻塞性肺病(OLIN)研究中,一组学龄儿童从8岁开始随访至19岁。在当前研究中,样本包括266名经医生诊断为哮喘且在15岁时过去12个月内有喘息或使用哮喘药物的青少年。
15岁时,报告学校中哮喘病情恶化的青少年的HRQoL得分较低(标准化β系数(β)= -0.18,P = 0.003),他们有更多与哮喘相关的担忧(β = -0.33,P < 0.001),且哮喘对其活动期间生活的影响更大(β = -0. —— 此处原文有误,应为β = -0.46,P < 0.001),高于哮喘未恶化的青少年。此外,青少年报告15岁时学校中哮喘恶化的情况越多,则与哮喘在15至19岁期间对其活动干扰程度的增加关联越大(β = 0.14,P = 0.038)。
学校中哮喘病情恶化与哮喘青少年的较低一般健康相关生活质量、较高的哮喘相关担忧及对日常活动的影响有关。