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衰老与情感障碍:1969 - 1978年苏格兰情感障碍首次发病年龄

Ageing and affective disorders: the age at first onset of affective disorders in Scotland, 1969-1978.

作者信息

Eagles J M, Whalley L J

出版信息

Br J Psychiatry. 1985 Aug;147:180-7. doi: 10.1192/bjp.147.2.180.

DOI:10.1192/bjp.147.2.180
PMID:4041692
Abstract

First admission rates from 1969-78 for Scottish psychiatric units were calculated for discharge diagnoses of affective psychosis for each five-year age-group from 15 years to over 74 years. There were clear-cut linear increases in rates of depressive psychoses, mania, and all affective psychoses, consistent with a relatively steady increase in the rate of first-onset affective psychoses with increasing age. These findings are discussed in terms of social, psychological, and biological hypotheses of the causes of affective disorder. It is argued that no single factor could produce the observed linear increases with age and that the data appear more consistent with an integrative aetiological model of affective disorder.

摘要

计算了1969年至1978年苏格兰精神科病房针对15岁至74岁以上各五年年龄组情感性精神病出院诊断的首次入院率。抑郁性精神病、躁狂症及所有情感性精神病的发病率均呈明显的线性增长,这与首次发作的情感性精神病发病率随年龄增长相对稳定增加相一致。从情感障碍病因的社会、心理和生物学假说角度对这些发现进行了讨论。有人认为,没有单一因素能导致观察到的随年龄增长的线性增加,而且这些数据似乎更符合情感障碍的综合病因模型。

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