Joshi Madhura, Patil Shruthi B
Pediatric and Preventive Dentistry, Sri Dharmasthala Manjunatheshwara (SDM) Dental College of Dental Sciences & Hospital, Sattur, Dharwad, Karnataka, India.
GMS Hyg Infect Control. 2025 Apr 28;20:Doc12. doi: 10.3205/dgkh000541. eCollection 2025.
Early childhood caries (ECC) is a chronic, infectious disease affecting young children. Though several preventive methods/measures are, the awareness about the benefits of a Ayurvedic preparation and its limited side effects is high. Thus, aim of this study was to compare efficacy of Ayurvedic formulations in reduction of the micro-organism causing ECC.
In a double-blind randomized, placebo-controlled trial 60 children between 6 and 71 months age with ECC were divided into group I (n=20, control group), group II (n=20, group) and group III (n=20, HiOra group). Unstimulated saliva was collected pre and after 16 day post mouthrinse. The baseline microbiological colony count was performed for and Lactobacillus spp. The results obtained were statistically analysed using non parametric test.
There was significant reduction in the amount of colony-forming units (cfu) between the control and the treatment groups. In the HiOra group the reduction of cfu was tendentially greater (p>0.05) than in the group. In the HiOra group only significant reduction of was seen, whereas in the group significant reduction of and Lactobacillus spp. was seen.
Reduction in total microorganisms was less significant among the experimental groups. However the reduction in total colony count was greater in HiOra followed by and the control group showed lesser reduction value.
幼儿龋齿（ECC）是一种影响幼儿的慢性传染病。尽管有几种预防方法/措施，但人们对阿育吠陀制剂的益处及其有限的副作用的认知度很高。因此，本研究的目的是比较阿育吠陀制剂在减少导致ECC的微生物方面的疗效。
在一项双盲随机、安慰剂对照试验中，60名年龄在6至71个月之间患有ECC的儿童被分为第一组（n = 20，对照组）、第二组（n = 20，[此处原文缺失组名]组）和第三组（n = 20，HiOra组）。在漱口前和漱口后16天收集非刺激性唾液。对[此处原文缺失相关微生物名称]和乳酸杆菌属进行基线微生物菌落计数。使用非参数检验对所得结果进行统计分析。
对照组和治疗组之间的菌落形成单位（cfu）数量有显著减少。在HiOra组中，cfu的减少趋势比[此处原文缺失组名]组更大（p>0.05）。在HiOra组中，仅观察到[此处原文缺失相关微生物名称]的显著减少，而在[此处原文缺失组名]组中，观察到[此处原文缺失相关微生物名称]和乳酸杆菌属的显著减少。
实验组中总微生物的减少不太显著。然而，HiOra组中总菌落数的减少更大，其次是[此处原文缺失组名]组，对照组的减少值较小。
