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自粘性GC金标混合树脂与抗生素改性玻璃离子水门汀的氟释放/摄取及物理性能的比较评价：一项研究。

Comparative Evaluation of Fluoride Release/Uptake and Physical Properties of Self-adhesive GC Gold Label Hybrid and Antibiotic-modified Glass Ionomer Cement: An Study.

作者信息

Done Vasanthi, Battu Satyakeerthana, Prasad Madhu Ghanasyam, Sahana Suzan, Kanaparthi Saraswathi

机构信息

Department of Pediatric and Preventive Dentistry, Mamata Dental College, Khammam, Telangana, India.

Private Practitioner, Lifekare Dental Hospital, Hyderabad, Telangana, India.

出版信息

Int J Clin Pediatr Dent. 2025 Feb;18(2):146-152. doi: 10.5005/jp-journals-10005-3052. Epub 2025 Mar 20.

DOI:10.5005/jp-journals-10005-3052
PMID:40417432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12099261/
Abstract

BACKGROUND

Scientific research continues to make progress in identifying the best practices for treating and preventing dental caries. The quest to search for an ideal restorative material has been a challenge for researchers and academicians in the fraternity of restorative dentistry.

MATERIALS AND METHODS

A total of 90 restorative specimens were prepared and divided into two groups comprising 45 samples each: gold label hybrid (group I) and antibiotic-modified glass ionomer cement (GIC) (group II). Each group was further subdivided into three groups of 15 samples each for the evaluation of compressive strength, setting time, and fluoride release, respectively. GC label hybrid was designated as group I, and an antibiotic mixture consisting of ciprofloxacin and metronidazole (1:1) was added at 1% concentration to conventional GIC (Fuji II), which served as group II. The compressive strength was evaluated using a universal testing machine with a crosshead speed of 1 mm/minute. The setting time was measured using Vicat's apparatus. Fluoride release was evaluated using an ion-selective electrode. The data were statistically analyzed.

RESULTS

The results showed a -value of 0.001, signifying a statistically significant difference between the two groups in terms of compressive strength, setting time, and fluoride release after 24 hours and after 1 week.

CONCLUSION

It can be concluded that antibiotic-modified GIC showed the best performance with improved characteristics, such as higher compressive strength, faster setting time, and enhanced fluoride release.

HOW TO CITE THIS ARTICLE

Done V, Battu S, Prasad MG, Comparative Evaluation of Fluoride Release/Uptake and Physical Properties of Self-adhesive GC Gold Label Hybrid and Antibiotic-modified Glass Ionomer Cement: An Study. Int J Clin Pediatr Dent 2025;18(2):146-152.

摘要

背景

科学研究在确定治疗和预防龋齿的最佳方法方面不断取得进展。寻找理想的修复材料一直是修复牙科领域研究人员和学者面临的挑战。

材料与方法

共制备了90个修复标本，分为两组，每组45个样本：金标混合材料（第一组）和抗生素改性玻璃离子水门汀（GIC）（第二组）。每组再进一步细分为三组，每组15个样本，分别用于评估抗压强度、凝固时间和氟释放。GC标混合材料被指定为第一组，将环丙沙星和甲硝唑（1:1）组成的抗生素混合物以1%的浓度添加到传统GIC（富士II型）中作为第二组。使用十字头速度为1毫米/分钟的万能试验机评估抗压强度。使用维卡仪测量凝固时间。使用离子选择性电极评估氟释放。对数据进行统计学分析。

结果

结果显示P值为0.001，表明两组在24小时和1周后的抗压强度、凝固时间和氟释放方面存在统计学上的显著差异。

结论

可以得出结论，抗生素改性GIC表现出最佳性能，具有更高的抗压强度、更快的凝固时间和增强的氟释放等改进特性。

如何引用本文

多内V、巴图S、普拉萨德MG，自粘性GC金标混合材料与抗生素改性玻璃离子水门汀氟释放/吸收及物理性能的比较评价：一项研究。《国际临床儿科牙科杂志》2025年；18（2）：146 - 152。

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