Yermalkar Gaurav S, Devendrappa Shashikiran N, Gaonkar Namrata N, Gugawad Sachin, Hadakar Savita, Waghmode Sonali K, Maurya Ankita
Department of Pediatric and Preventive Dentistry, School of Dental Sciences, Krishna Vishwa Vidyapeeth, Karad, Satara, Maharashtra, India.
Department of Pedodontics and Preventive Dentistry, School of Dental Sciences, Krishna Vishwa Vidyapeeth, Satara, Maharashtra, India.
Int J Clin Pediatr Dent. 2025 Feb;18(2):167-172. doi: 10.5005/jp-journals-10005-3059. Epub 2025 Mar 20.
Glass ionomer cement (GIC) is an excellent example of dental materials that revolutionized the way we approach restorative dentistry. There have been several studies aimed at improving the properties of GIC while reducing its compressive strength, brittleness, etc.Over time, to combat this cumbersome problem, various agents have been added to GIC to increase its antimicrobial properties. The incorporation of fluoride, selenium, and other compounds has proven to reduce the rate of formation of cariogenic biofilm. However, the use of synthetic compounds such as fluoride can result in fluorosis. This calls for the need for a natural antimicrobial agent with minimal or no side effects and optimal effectiveness.Grape seed extract (GSE) and resveratrol (grape skin extract) are naturally occurring compounds having antibacterial, anti-inflammatory, and antioxidative properties.
GSE and resveratrol were incorporated into conventional restorative GIC.Conventional and experimental restorative GICs were manipulated according to manufacturer instructions and were then tested for their compressive strength, shear bond strength (SBS), and fluoride release.
Mean compressive strength was highest for GIC incorporated with GSE, followed by resveratrol incorporated GIC, with the least being in the control group. Mean SBS and fluoride release were highest in resveratrol incorporated GIC, followed by GSE incorporated GIC, with the least being in the control group.
Positive results were observed, showing an increase in the properties of fluoride release, SBS, and compressive strength in GIC incorporated with plant-based extracts.
GIC is routinely used in pediatric dentistry, requiring constant evolution to improve its properties. The incorporation of plant-based extracts in GIC is a natural alternative to synthetic additives while also enhancing its physical properties. Further studies are required to assess the long-term effect of the experimental adhesives in clinical trials.
Yermalkar GS, Devendrappa SN, Gaonkar NN, Comparative Evaluation of Compressive Strength, Shear Bond Strength, and Fluoride Release of Grape Seed Extract and Resveratrol Incorporated in Conventional Restorative Glass Ionomer Cement: An Study. Int J Clin Pediatr Dent 2025;18(2):167-172.
玻璃离子水门汀（GIC）是牙科材料中的一个杰出范例，它彻底改变了我们进行修复牙科治疗的方式。已有多项研究旨在改善GIC的性能，同时降低其抗压强度、脆性等。随着时间的推移，为解决这个棘手的问题，人们向GIC中添加了各种试剂以增强其抗菌性能。氟化物、硒及其他化合物的加入已证明可降低致龋生物膜的形成速率。然而，使用氟化物等合成化合物可能会导致氟牙症。这就需要一种副作用极小或无副作用且效果最佳的天然抗菌剂。葡萄籽提取物（GSE）和白藜芦醇（葡萄皮提取物）是具有抗菌、抗炎和抗氧化特性的天然化合物。
将GSE和白藜芦醇加入传统修复性GIC中。按照制造商说明操作传统和实验性修复性GIC，然后测试其抗压强度、剪切粘结强度（SBS）和氟释放量。
加入GSE的GIC平均抗压强度最高，其次是加入白藜芦醇的GIC，对照组最低。加入白藜芦醇的GIC平均SBS和氟释放量最高，其次是加入GSE的GIC，对照组最低。
观察到了积极结果，表明加入植物提取物的GIC在氟释放、SBS和抗压强度方面的性能有所提高。
GIC常用于儿童牙科，需要不断改进以提高其性能。在GIC中加入植物提取物是合成添加剂的天然替代品，同时还能增强其物理性能。需要进一步研究以评估实验性粘结剂在临床试验中的长期效果。
Yermalkar GS, Devendrappa SN, Gaonkar NN, 传统修复性玻璃离子水门汀中加入葡萄籽提取物和白藜芦醇的抗压强度、剪切粘结强度和氟释放的比较评价：一项研究。《国际临床儿科牙科学杂志》2025年；18(2):167 - 172。
