Levine M S, Hannigan J H, Fisher R S, Howard-Butcher S, Hull C D, Buchwald N A
Brain Res. 1985 Sep;354(1):150-5. doi: 10.1016/0165-3806(85)90079-3.
The development of the behavioral effects of amphetamine was assessed in kittens of 1-53 days of age. Amphetamine-induced increases in locomotion occurred when animals were beyond 35 days of age. Stereotypic behavior was induced at all ages tested but the predominant type of stereotypy was age-related. From 1 to 14 days amphetamine induced licking. Pendular head movements occurred when animals were under 35 days. At 14 days of age darting, a response consisting of rapid pacing and turning began to occur. Tracking, a series of horizontal and vertical head movements also began to occur after 14 days. The adult response of vertical and horizontal head movements became most prominent after 35 days.
评估了1至53日龄小猫中苯丙胺行为效应的发展情况。当动物超过35日龄时,苯丙胺会引起运动增加。在所有测试年龄都能诱导出刻板行为,但刻板行为的主要类型与年龄有关。1至14日龄时,苯丙胺诱导舔舐行为。35日龄以下的动物会出现摆动头部动作。14日龄时开始出现突进,这是一种由快速踱步和转身组成的反应。追踪,即一系列水平和垂直头部动作,在14日龄后也开始出现。35日龄后,成年动物垂直和水平头部动作的反应最为明显。