静态眼顺应性的测量装置及推导公式。
Measurement device and derivation formula for static ocular compliance.
作者信息
Wang Suchang, Si Shancheng, Hou Wenwen, Zhang Ming, Zhang Guimin
机构信息
State Key Laboratory of Intelligent Construction and Healthy Operation, Maintenance of Deep Underground Engineering, School of Mechanics and Civil Engineering, China University of Mining and Technology, No. 1 University Road, Quanshan District, Xuzhou, 221116, Jiangsu, China.
The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou, 221116, Jiangsu, China.
出版信息
Sci Rep. 2025 May 26;15(1):18305. doi: 10.1038/s41598-025-03415-8.
To introduce a device for measuring static ocular compliance (SOC) and propose a best-fit formula. An observational experimental study involving patients with age-related cataracts was conducted between May 2024 and September 2024. Pearson's correlation analysis was used to screen for potential variables that were significantly associated with the SOC. Then, the SOC at six different height differences (recorded as "Δh") was compared, and the best-fit equations for SOC were screened by linear regression analysis. C was defined as SOC at height difference of Δh mm. A total of 47 eyes of 47 patients (22 males [46.8%] and 25 females [53.2%]) were enrolled. The mean SOC was (0.846 ± 0.274) µL/cmHO, with a 95% confidence interval of (0.813-0.879) µL/cmHO, with ocular axial length (AL) of (23.74 ± 1.83) mm and central corneal thickness of (541.13 ± 35.34) µm. Furthermore, Pearson's correlation analysis revealed a significant correlation between SOC and AL (all P < 0.001). Using our device, the best-fit formula can be expressed as SOC = 0.948 x C + 0.067 x AL (R = 0.985; P = 0.000), with an optimal height difference of 600 mm. The designed in vivo measurement device can accurately measure SOC and derive a best-fit formula.
介绍一种测量静态眼顺应性（SOC）的装置并提出最佳拟合公式。于2024年5月至2024年9月进行了一项涉及年龄相关性白内障患者的观察性实验研究。采用Pearson相关性分析筛选与SOC显著相关的潜在变量。然后，比较六个不同高度差（记录为“Δh”）下的SOC，并通过线性回归分析筛选SOC的最佳拟合方程。C定义为高度差为Δh毫米时的SOC。共纳入47例患者的47只眼（男性22例[46.8%]，女性25例[53.2%]）。平均SOC为（0.846±0.274）µL/cmHO，95%置信区间为（0.813 - 0.879）µL/cmHO，眼轴长度（AL）为（23.74±1.83）mm，中央角膜厚度为（541.13±35.34）µm。此外，Pearson相关性分析显示SOC与AL之间存在显著相关性（所有P<0.001）。使用我们的装置，最佳拟合公式可表示为SOC = 0.948×C + 0.067×AL（R = 0.985；P = 0.000），最佳高度差为600毫米。所设计的体内测量装置能够准确测量SOC并得出最佳拟合公式。
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