Wang Rui, Tan Jianyu, Su Zhewei, Kong Yiting, Hong Su, Ran Pan, Zhong Yuancen, Kuang Li
Psychiatric Center, The First Affiliated Hospital of Chongqing Medical University, Yuzhong District, Chongqing, 400016, China.
Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
BMC Public Health. 2025 May 26;25(1):1931. doi: 10.1186/s12889-025-23128-x.
Evidence on the dose-response connection involving depressive symptoms and various types of physical activity in urban and rural populations is scarce. This study compares the dose-response connection across depressive symptoms and different types of activity in populations living in rural and urban areas.
The study is based on a cross-sectional weighted sample from the 2020 China Health and Retirement Longitudinal Study (CHARLS). Physical activity and depressive symptoms were assessed using self-reported activity from the CHARLS questionnaire and the Centre for Epidemiological Studies Depression Scale. Physical activity was computed in metabolic equivalents (METs) and depressive symptom cutoff is 10. 1 MET is the amount of oxygen used during rest (3.5 mL O2/kg/min). Multivariate logistic regression analyses were used to determine the dose-response relationship between different types of physical activity and depressive symptoms.
Physical activity of different types showed a varying relationship with depressive symptoms with dose in rural populations. However, in urban populations, recreational physical activity exhibited a negative correlation with depressive symptoms, while non-recreational activity displayed a positive correlation. Specifically, in the rural population, 600-3,000 METs-min/week of recreational physical activity was inversely linked to depressive symptoms, but recreational physical activity exceeding 3,000 METs-min/week was associated with a 13.2% risk increase in depressive symptoms (OR = 1.132, 95% CI: 1.131-1.132), and over 6,000 METs-min/week of non-recreational activity was similarly associated with an increased risk of depressive symptoms. In the urban population, recreational physical activity was related to a reduced incidence of depressive symptoms, with a maximum reduction of 71.7% at doses up to 9,000-12,000 METs min/week (OR = 0.283, 95% CI:0.282-0.284), and 6,000-9,000 non-recreational physical activities, the odds of increased risk of depressive symptoms were highest (OR = 2.224, 95% CI:2.221-2.227).
Our study found a non-linear dose correlation between physical activities and depressive symptoms. The dose-response connection between different physical activity types and depressive symptoms varies between rural and urban areas. Recreational physical activity is recommended for urban and reasonable amounts of nonrecreational physical activity for rural populations to reduce the risk of depressive symptoms. However, causal interpretations cannot be made due to the cross-sectional design of the study.
关于城乡人口中抑郁症状与各类身体活动之间剂量反应关系的证据匮乏。本研究比较了城乡地区人群中抑郁症状与不同类型活动之间的剂量反应关系。
本研究基于2020年中国健康与养老追踪调查(CHARLS)的横断面加权样本。使用CHARLS问卷中的自我报告活动和流行病学研究中心抑郁量表评估身体活动和抑郁症状。身体活动以代谢当量(METs)计算,抑郁症状临界值为10。1个MET是休息时消耗的氧量(3.5毫升氧气/千克/分钟)。采用多因素逻辑回归分析确定不同类型身体活动与抑郁症状之间的剂量反应关系。
不同类型的身体活动与农村人群中抑郁症状的剂量呈现出不同的关系。然而,在城市人群中,休闲身体活动与抑郁症状呈负相关,而非休闲活动则呈正相关。具体而言,在农村人群中,每周600 - 3000 METs - 分钟的休闲身体活动与抑郁症状呈负相关,但每周超过3000 METs - 分钟的休闲身体活动与抑郁症状风险增加13.2%相关(比值比=1.132,95%置信区间:1.131 - 1.132),每周超过6000 METs - 分钟的非休闲活动同样与抑郁症状风险增加相关。在城市人群中,休闲身体活动与抑郁症状发病率降低相关,在每周剂量高达9000 - 12000 METs - 分钟时最大降低率为71.7%(比值比=0.283,95%置信区间:0.282 - 0.284),而6000 - 9000 METs - 分钟的非休闲身体活动,抑郁症状风险增加的几率最高(比值比=2.224,95%置信区间:2.221 - 2.227)。
我们的研究发现身体活动与抑郁症状之间存在非线性剂量相关性。不同类型身体活动与抑郁症状之间的剂量反应关系在城乡地区有所不同。建议城市人群进行休闲身体活动,农村人群进行适量的非休闲身体活动以降低抑郁症状风险。然而,由于本研究的横断面设计,无法进行因果推断。