Iryivuze Olivier, Olasinde Anthony Ayotunde, Favina Alain, Muhumuza Joshua, Emeka Anyanwu Godson, Kiswezi Ahmed
Department of Surgery, Faculty of Clinical Medicine and Dentistry, Kampala International University, Western Campus, Bushenyi, Uganda.
Department of Orthopaedic Surgery, Federal Medical Center, Owo, Ondo State, Nigeria.
BMC Musculoskelet Disord. 2025 May 26;26(1):518. doi: 10.1186/s12891-025-08757-y.
Acute compartment syndrome (ACS) is a devastating and time-sensitive emergency that increases limb disabilities, amputations, and deaths annually. However, there is a paucity of data on the incidence of ACS in tibia fractures and its predictors in Uganda that can help us save the limb. This study aimed to determine the incidence of ACS in tibia fractures and its predictors in Uganda.
A prospective cohort study was conducted for 6 months at three tertiary hospitals in Uganda where patients with tibia fractures were examined clinically and had their intracompartmental pressure (ICP) measured for ACS using the Whitesides technique, with a 24-hour follow-up after admission and after orthopaedic treatment. All patients were managed as per the ATLS protocol; Data were analyzed using SPSS version 22.
The study enrolled 130 study participants with tibia fracture. The majority of participants were males (76.9%). The age group of 18-30 years made up 55.4%. The incidence of ACS was found to be 8.5% (11/130). Among the 11 people with ACS, all had both tibia and fibula fractures, and 8/11 had closed fractures. Smoking (aRR = 2.189, CI = 1.614-7.812, P = 0.049) and swelling of the injured limb (aRR = 3.793, CI = 1.479-9.727, P = 0.008) were the independent predictors of ACS.
The incidence of ACS in Uganda was 8.5%. People with a history of cigarette smoking and clinical symptoms of swelling of the limb should be monitored more closely.
Not applicable.
急性骨筋膜室综合征（ACS）是一种严重且对时间敏感的急症，每年都会增加肢体残疾、截肢和死亡的发生率。然而，关于乌干达胫骨骨折中急性骨筋膜室综合征的发病率及其预测因素的数据匮乏，而这些数据有助于我们保住肢体。本研究旨在确定乌干达胫骨骨折中急性骨筋膜室综合征的发病率及其预测因素。
在乌干达的三家三级医院进行了为期6个月的前瞻性队列研究，对胫骨骨折患者进行临床检查，并使用Whitesides技术测量其骨筋膜室内压力（ICP）以诊断急性骨筋膜室综合征，在入院后和骨科治疗后进行24小时随访。所有患者均按照高级创伤生命支持（ATLS）方案进行处理；使用SPSS 22版软件进行数据分析。
该研究纳入了130名胫骨骨折的研究参与者。大多数参与者为男性（76.9%）。18至30岁年龄组占55.4%。发现急性骨筋膜室综合征的发病率为8.5%（11/130）。在11例急性骨筋膜室综合征患者中，均为胫腓骨骨折，11例中有8例为闭合性骨折。吸烟（调整后相对危险度[aRR]=2.189，可信区间[CI]=1.614 - 7.812，P=0.049）和受伤肢体肿胀（aRR=3.793，CI=1.479 - 9.727，P=0.008）是急性骨筋膜室综合征的独立预测因素。
乌干达急性骨筋膜室综合征的发病率为8.5%。有吸烟史和肢体肿胀临床症状的人群应进行更密切的监测。
不适用。
