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本文引用的文献

1
Efficacy of sound therapy interventions for tinnitus management: A protocol for systematic review and network meta-analysis.声疗干预治疗耳鸣的疗效:系统评价和网络荟萃分析方案。
Medicine (Baltimore). 2021 Oct 15;100(41):e27509. doi: 10.1097/MD.0000000000027509.
2
Review of Pharmacotherapy for Tinnitus.耳鸣的药物治疗综述
Healthcare (Basel). 2021 Jun 21;9(6):779. doi: 10.3390/healthcare9060779.
3
The effect of tinnitus retraining therapy on chronic tinnitus: A controlled trial.耳鸣再训练疗法对慢性耳鸣的疗效:一项对照试验。
Laryngoscope Investig Otolaryngol. 2017 May 28;2(4):166-177. doi: 10.1002/lio2.76. eCollection 2017 Aug.
4
Psychometric properties of the Tinnitus Functional Index (TFI): Assessment in a UK research volunteer population.耳鸣功能指数(TFI)的心理测量特性:在英国研究志愿者群体中的评估。
Hear Res. 2016 May;335:220-235. doi: 10.1016/j.heares.2015.09.009. Epub 2015 Sep 28.
5
The relationship of perceived severity of tinnitus with depression, anxiety, hearing status, age and gender in individuals with tinnitus.耳鸣患者中耳鸣感知严重程度与抑郁、焦虑、听力状况、年龄及性别的关系。
Int Tinnitus J. 2013;18(1):29-34. doi: 10.5935/0946-5448.20130005.
6
A randomized double-blind crossover study of phase-shift sound therapy for tinnitus.一项针对相位转换声疗法治疗耳鸣的随机双盲交叉研究。
Otolaryngol Head Neck Surg. 2012 Aug;147(2):308-15. doi: 10.1177/0194599812442615. Epub 2012 Mar 30.
7
PHARMACOLOGICAL TREATMENTS FOR TINNITUS: NEW AND OLD.耳鸣的药物治疗:新旧方法
Drugs Future. 2009;34(5):381-400. doi: 10.1358/dof.2009.034.05.1362442.
8
Open ear hearing aids in tinnitus therapy: An efficacy comparison with sound generators.耳鸣治疗中的开放式耳助听器:与声音发生器的疗效比较。
Int J Audiol. 2011 Aug;50(8):548-53. doi: 10.3109/14992027.2011.572263. Epub 2011 May 19.
9
Effects of acoustical stimuli delivered through hearing aids on tinnitus.通过助听器传递的声学刺激对耳鸣的影响。
J Am Acad Audiol. 2010 Jul-Aug;21(7):461-73. doi: 10.3766/jaaa.21.7.5.
10
Tinnitus outcomes assessment.耳鸣结果评估。
Trends Amplif. 2008 Sep;12(3):223-35. doi: 10.1177/1084713808319943. Epub 2008 Jul 3.

慢性耳鸣患者治疗效果评估:一项双向队列研究。

Assessment of Treatment Efficacy in Patients with Chronic Tinnitus: An Ambispective Cohort Study.

作者信息

Sankar Sakthimurugan, Sekar Raghul, Anbarasan Subagar, Haritha S

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, Tamil Nadu India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 Jun;77(6):2277-2282. doi: 10.1007/s12070-025-05478-5. Epub 2025 May 7.

DOI:10.1007/s12070-025-05478-5
PMID:40420882
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12103438/
Abstract

INTRODUCTION

Tinnitus, a subjective perception of sound without external stimuli, affects millions worldwide, impairing daily function and quality of life. The severity of tinnitus is influenced by associated symptoms such as stress, anxiety, depression, and insomnia. The Tinnitus Functional Index (TFI) is a validated tool for assessing tinnitus severity and treatment outcomes. Despite the lack of a definitive cure, multimodal treatments, including pharmacotherapy and Tinnitus Retraining Therapy (TRT), show promise in managing the condition.

AIM

This ambispective cohort study aimed to evaluate treatment efficacy in chronic tinnitus patients without hearing loss, using the Tinnitus Functional Index (TFI) as an assessment tool.

METHODOLOGY

Forty patients were divided into two groups: Group A received pharmacological treatment alone, while Group B received both pharmacological treatment and tinnitus retraining therapy (TRT). TFI scores were recorded at baseline, 3, 6, and 12 months.

RESULTS

Statistical analyses revealed significant improvements in TFI scores in both groups over time, with Group B demonstrating greater improvement, indicating the efficacy of TRT.

CONCLUSION

Our findings underscore the importance of multimodal treatment approaches, particularly TRT, in managing chronic tinnitus without hearing loss. Further research is warranted to refine treatment protocols and enhance patient outcomes.

摘要

引言

耳鸣是一种在无外部刺激情况下的主观声音感知,全球数以百万计的人受其影响,损害日常功能和生活质量。耳鸣的严重程度受压力、焦虑、抑郁和失眠等相关症状的影响。耳鸣功能指数(TFI)是评估耳鸣严重程度和治疗效果的有效工具。尽管缺乏确切的治愈方法,但包括药物治疗和耳鸣再训练疗法(TRT)在内的多模式治疗在控制病情方面显示出前景。

目的

这项前瞻性队列研究旨在使用耳鸣功能指数(TFI)作为评估工具,评估无听力损失的慢性耳鸣患者的治疗效果。

方法

40名患者分为两组:A组仅接受药物治疗,而B组接受药物治疗和耳鸣再训练疗法(TRT)。在基线、3个月、6个月和12个月时记录TFI评分。

结果

统计分析显示,两组的TFI评分随时间均有显著改善,B组改善更大,表明TRT的疗效。

结论

我们的研究结果强调了多模式治疗方法,特别是TRT,在管理无听力损失的慢性耳鸣中的重要性。有必要进一步研究以完善治疗方案并改善患者预后。