J Am Dent Assoc. 2023 Jul;154(7):567-579. doi: 10.1016/j.adaj.2023.03.004. Epub 2023 May 18.
This scoping review and analysis were designed to assess the amount of time spent delivering photobiomodulation (PBM) light therapy after dental extraction to improve postoperative pain and wound healing.
The scoping review was performed according to the Cochrane Collaboration and Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Publications were specific for human randomized controlled clinical trials, PBM after dental extraction therapy, and related clinical outcomes. Online databases searched included PubMed, Embase, Scopus, and Web of Science. Analyses were conducted to analyze the prescribed intervals of time (seconds) per application of PBM.
Of the 632 studies initially identified, 22 studies fulfilled the inclusion criteria. Postoperative pain and PBM were reported in 20 articles for 24 treatment groups, with treatment times ranging from 17 through 900 seconds and wavelengths from 550 through 1,064 nm. Clinical wound healing outcomes were reported in 6 articles for 7 groups with treatment times ranging from 30 through 120 seconds and wavelengths from 660 through 808 nm. PBM therapy was not associated with adverse events.
There is future potential to integrate PBM after dental extraction therapy to improve postoperative pain and clinical wound healing. The amount of time spent delivering PBM will vary by wavelength and the type of device. Further investigation is needed to translate PBM therapy into human clinical care.
本范围界定审查和分析旨在评估在拔牙后进行光生物调节（PBM）光疗以改善术后疼痛和伤口愈合所需的时间。
该范围界定审查是根据 Cochrane 协作组织和系统评价与荟萃分析的首选报告项目标准进行的。出版物是专门针对人类随机对照临床试验、拔牙后 PBM 治疗和相关临床结果的。在线数据库检索包括 PubMed、Embase、Scopus 和 Web of Science。分析用于分析 PBM 每次应用的规定时间（秒）。
最初确定的 632 项研究中，有 22 项符合纳入标准。20 篇文章报告了术后疼痛和 PBM，涉及 24 个治疗组，治疗时间从 17 秒到 900 秒，波长从 550 纳米到 1064 纳米不等。6 篇文章报告了 7 个组的临床伤口愈合结果，治疗时间从 30 秒到 120 秒，波长从 660 纳米到 808 纳米不等。PBM 治疗与不良事件无关。
将 PBM 整合到拔牙后治疗中以改善术后疼痛和临床伤口愈合具有未来潜力。输送 PBM 的时间将因波长和设备类型而异。需要进一步研究将 PBM 治疗转化为人类临床护理。
