Godbout R, Montplaisir J, Rouleau I
Clin Electroencephalogr. 1985 Jul;16(3):136-42. doi: 10.1177/155005948501600307.
A patient was studied who every night experienced several attacks characterized by loud screaming, violent movements of limbs and trunk, and a tonic phase. No epileptiform activity was noted preceding or following these attacks. Prolonged EEG and videotape recordings before and after sleep deprivation, along with neuropsychological and pharmacological data, support the hypothesis of a seizure disorder involving the left temporal region. Nocturnal attacks completely disappeared with carbamazepine. This therapeutic effect was still present after six months of treatment. Sleep organization was also greatly influenced by this medication. The most striking change was the marked and sustained increase of stages 3 and 4 NREM sleep after treatment.
对一名患者进行了研究，该患者每晚经历几次发作，其特征为大声尖叫、四肢和躯干剧烈运动以及强直期。在这些发作之前或之后均未发现癫痫样活动。睡眠剥夺前后的长时间脑电图和录像记录，以及神经心理学和药理学数据，支持了涉及左颞叶区域的癫痫发作障碍的假说。夜间发作在使用卡马西平后完全消失。治疗六个月后，这种治疗效果仍然存在。这种药物对睡眠结构也有很大影响。最显著的变化是治疗后3期和4期非快速眼动睡眠显著且持续增加。
