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表现为日间过度嗜睡的发作性夜间肌张力障碍。

Paroxysmal nocturnal dystonia presenting as excessive daytime somnolence.

作者信息

Maccario M, Lustman L I

机构信息

Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco, Calif. 94129-6700.

出版信息

Arch Neurol. 1990 Mar;47(3):291-4. doi: 10.1001/archneur.1990.00530030061017.

Abstract

We describe the clinical and electrophysiologic findings in seven patients referred for evaluation of excessive daytime somnolence. These patients had none of the usual causes of excessive daytime somnolence but during sleep exhibited stereotypic body movements, tachycardia, respiratory disturbances, somniloquy, and transient arousals in a repetitive fashion. These episodes induced fragmentation of sleep. The polysomnograms revealed an increase in wakefulness and stage I decreased rapid eye movement during sleep in addition to the episodes of abnormal body movements. No epileptiform features were present either in the electroencephalogram or in the nocturnal polysomnogram. Four of the seven patients were treated with anticonvulsants, with both subjective and objective improvement on subsequent follow-up polysomnograms. Because of the pronounced functional deficits associated with the sleep disorder in these patients, it is of great importance to recognize the disorder and treat it appropriately.

摘要

我们描述了七名因日间过度嗜睡前来评估的患者的临床和电生理检查结果。这些患者没有导致日间过度嗜睡的常见原因,但在睡眠期间会反复出现刻板的身体运动、心动过速、呼吸紊乱、说梦话和短暂觉醒。这些发作导致睡眠碎片化。多导睡眠图显示,除了异常身体运动发作外,清醒时间增加,睡眠期间快速眼动期减少。脑电图或夜间多导睡眠图均未出现癫痫样特征。七名患者中有四名接受了抗惊厥药物治疗,后续随访多导睡眠图显示主观和客观上均有改善。由于这些患者的睡眠障碍伴有明显的功能缺陷,认识到这种障碍并进行适当治疗非常重要。

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