一种流产布鲁氏菌制剂的抗肿瘤活性。
Antitumor activity of a Brucella abortus preparation.
作者信息
Keleti G, Feingold D S, Youngner J S
出版信息
Infect Immun. 1977 Mar;15(3):846-9. doi: 10.1128/iai.15.3.846-849.1977.
Abstract
Mice injected intraperitoneally with sarcoma-180 cells develop ascites and eventually die. Intraperitoneal injection of a nonviable, aqueous... ether-extracted Brucella abortus preparation (BRU-PEL) as early as 7 days before or as late as 7 days after injection of tumor cells significantly inhibited development of ascites and protected against death. BRU-PEL was not effective if injected after ascites was grossly apparent. BRU-PEL was significantly more active than a Corynebacterium parvum preparation administered in the same way.
摘要
经腹腔注射肉瘤 - 180细胞的小鼠会出现腹水并最终死亡。早在注射肿瘤细胞前7天或晚至注射后7天经腹腔注射一种灭活的、经水……乙醚提取的流产布鲁氏菌制剂（BRU - PEL），可显著抑制腹水的形成并预防死亡。如果在腹水明显出现后注射，BRU - PEL则无效。BRU - PEL的活性明显高于以相同方式给药的短小棒状杆菌制剂。
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