Rusu Laura Cristina, Beschiu Laura Maria, Iacob Florin, Zaharia Claudia, Neuwirth Kevin, Bulut Ozgur, Ardelean Lavinia Cosmina
University Clinic of Oral Pathology, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Sq, Timisoara, 300041, Romania.
Department of Mathematics, West University of Timisoara, 4 Vasile Parvan Blvd, Timisoara, 300223, Romania.
Sci Rep. 2025 May 27;15(1):18487. doi: 10.1038/s41598-025-01204-x.
Craniofacial reconstruction and facial approximations are valuable resources in the fields of anthropometry, forensics and surgery. Their accuracy depends on the availability of population specific datasets and consistent research and focus on improving and updating these datasets over time. Our study focuses on bringing new normative data regarding the relationship between the upper lip and the upper anterior teeth in a sample of adult Western Romanian population. This retrospective study was conducted on 226 computed tomography scans from the existing patient database of the Emergency Municipal Hospital of Timisoara, being the first study of this kind to focus on the Romanian population. The patients were divided in six subgroups depending on age and sex. A total of ten landmarks were considered, eight in the frontal plane and two in the sagittal plane, five hard tissue and five soft tissue. The 3D Slicer free, open-source software was used for the analysis. The inter-landmark distances were measured and results were compared. The results of the present study show similar patterns of associations between the measured inter-landmark distances for men and women. According to the measurements, inter-landmark distances are larger in males, compared to females, in all age groups. The strong correlation between right and left inter-landmark distances demonstrates the obvious right-left symmetry of most cases. A positive association was found between the skeletal and soft tissue contour of the maxilla, specifically, between the upper anterior teeth and the upper lip.
颅面重建和面部近似在人体测量学、法医学和外科领域是宝贵的资源。它们的准确性取决于特定人群数据集的可用性，以及持续的研究，并随着时间的推移专注于改进和更新这些数据集。我们的研究重点是在罗马尼亚西部成年人群样本中提供有关上唇与上前牙之间关系的新的标准数据。这项回顾性研究是对蒂米什瓦拉市立急诊医院现有患者数据库中的226份计算机断层扫描进行的，这是同类研究中第一项关注罗马尼亚人群的研究。根据年龄和性别将患者分为六个亚组。总共考虑了十个标志点，八个在额平面，两个在矢状平面，五个硬组织标志点和五个软组织标志点。使用免费的开源软件3D Slicer进行分析。测量标志点间距离并比较结果。本研究结果显示，男性和女性测量的标志点间距离之间存在相似的关联模式。根据测量结果，在所有年龄组中，男性的标志点间距离均大于女性。左右标志点间距离之间的强相关性表明大多数病例具有明显的左右对称性。在上颌骨的骨骼和软组织轮廓之间，特别是在上前牙和上唇之间发现了正相关。
