Lecciso Flavia, Martis Chiara, Levante Annalisa
Department in Human and Social Sciences, University of Salento, 73100 Lecce, Italy.
Lab of Applied Psychology, Department in Human and Social Sciences, University of Salento, 73100 Lecce, Italy.
Brain Sci. 2025 May 15;15(5):506. doi: 10.3390/brainsci15050506.
Griffiths III is a child-friendly and play-oriented direct gold-standard measure of a 0-6-year-old child's developmental profile. It is a measure that helps practitioners in detecting the weaknesses in children who have an increased likelihood or a diagnosis of neurodevelopmental disorders, e.g., autism.
Following the PICO protocol, two research questions addressed the current systematic search and review (Prospero registration: CRD42024554286): (RQ1); (RQ2).
Six studies have been reviewed: three case-control studies, a case report study, and two studies examining the effectiveness of early autism-specific interventions. According to the study design, the methodological quality was evaluated using three standardised protocols: STROBE; JBI; CEC.
The results highlighted that the Language and Communication and Personal-Social-Emotional domains are the most impaired in autistic children and in those with an increased likelihood (RQ1). The results outlined that early target intervention enhanced the same domains (RQ2).
In conclusion, the findings highlight the importance of screening not only for autism traits but also for impairments in language, communication, and socio-emotional skills. The future direction of the results is discussed.
格里菲斯发育量表第三版是一种适合儿童且以游戏为导向的直接金标准测量工具，用于评估0至6岁儿童的发育状况。它有助于从业者发现那些神经发育障碍（如自闭症）患病可能性增加或已确诊的儿童的弱点。
遵循PICO方案，两个研究问题涉及当前的系统检索和综述（Prospero注册编号：CRD42024554286）：（研究问题1）；（研究问题2）。
已对六项研究进行了综述：三项病例对照研究、一项病例报告研究以及两项考察早期自闭症特异性干预效果的研究。根据研究设计，使用三种标准化方案对方法学质量进行评估：STROBE；JBI；CEC。
结果突出表明，语言与沟通以及个人 - 社会 - 情感领域在自闭症儿童和患病可能性增加的儿童中受损最为严重（研究问题1）。结果还表明，早期针对性干预改善了这些相同领域（研究问题2）。
总之，研究结果强调了不仅要筛查自闭症特征，还要筛查语言、沟通和社会情感技能损伤的重要性。同时对结果的未来方向进行了讨论。
