Tatsumi N, Tsuda I, Fujimoto K, Matsumoto H
Cytometry. 1985 Sep;6(5):395-400. doi: 10.1002/cyto.990060502.
A blood cell counter with a sheath flow system has been developed to eliminate the drawback of the Coulter type blood cell counter, namely, signal distortion caused by the cells passing through the electric aperture gate. With the new system, signal distortion was low and a near-normal distribution curve for erythrocytes and resin particles was obtained. The counter has a computer program for determining the red cell distribution width, which represents an actual size difference at 20% of the relative frequency of the distribution curve. This is independent of mean cell volume, and is considered to be of clinical importance. We examined the values in 2,300 healthy subjects and patients with various hematological disorders.
一种带有鞘流系统的血细胞计数器已被开发出来，以消除库尔特型血细胞计数器的缺点，即细胞通过电孔径门时引起的信号失真。使用新系统时，信号失真较低，并且获得了红细胞和树脂颗粒的近似正态分布曲线。该计数器有一个用于确定红细胞分布宽度的计算机程序，红细胞分布宽度代表分布曲线相对频率20%处的实际大小差异。这与平均细胞体积无关，并且被认为具有临床重要性。我们检查了2300名健康受试者和患有各种血液系统疾病患者的相关数值。
