Kaplan R M, Wilson D K, Hartwell S L, Merino K L, Wallace J P
Diabetes Care. 1985 Jul-Aug;8(4):343-8. doi: 10.2337/diacare.8.4.343.
High-density lipoprotein (HDL) cholesterol is known to be low in patients with diabetes mellitus. Low HDL levels are correlated with premature cardiovascular mortality in several major epidemiologic studies and many investigators believe increases in HDL cholesterol may reduce the risk of coronary heart disease. We evaluated dietary and exercise interventions in relation to HDL cholesterol in patients with type II diabetes mellitus. Sixty-five volunteers were randomly assigned to one of four experimental conditions: diet, exercise, diet plus exercise, or education control. Three months after entering the program, those exposed to the dietary intervention had significant increases in HDL cholesterol. HDL increases for the other two treatment groups did not differ significantly from the education control.
已知糖尿病患者的高密度脂蛋白（HDL）胆固醇水平较低。在几项主要的流行病学研究中，低HDL水平与心血管疾病过早死亡相关，许多研究人员认为，HDL胆固醇水平的升高可能会降低冠心病风险。我们评估了饮食和运动干预对II型糖尿病患者HDL胆固醇的影响。65名志愿者被随机分配到四种实验条件之一：饮食、运动、饮食加运动或教育对照。进入该项目三个月后，接受饮食干预的患者HDL胆固醇显著升高。其他两个治疗组的HDL升高与教育对照组无显著差异。
