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本文引用的文献

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Modified-Release Pulmonary Delivery Systems for Labile Bioactives: Design, Development, and Applications.用于不稳定生物活性物质的缓释肺部给药系统：设计、开发与应用
Pharmaceutics. 2025 Apr 3;17(4):470. doi: 10.3390/pharmaceutics17040470.
2
Nanostructures for drug delivery in respiratory diseases therapeutics: Revision of current trends and its comparative analysis.用于呼吸系统疾病治疗中药物递送的纳米结构：当前趋势综述及其比较分析
J Drug Deliv Sci Technol. 2022 Apr;70:103219. doi: 10.1016/j.jddst.2022.103219. Epub 2022 Mar 5.
3
A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases.用于治疗传染性肺病的肺部递药策略路线图。
J Nanobiotechnology. 2022 Mar 3;20(1):101. doi: 10.1186/s12951-022-01307-x.
4
Nano-delivery to the lung - by inhalation or other routes and why nano when micro is largely sufficient?纳米药物向肺部的递送——通过吸入或其他途径，以及在微米级药物基本足够的情况下为何还要使用纳米级药物？
Adv Drug Deliv Rev. 2022 Apr;183:114173. doi: 10.1016/j.addr.2022.114173. Epub 2022 Feb 22.
5
Strategies to Overcome Biological Barriers Associated with Pulmonary Drug Delivery.克服肺部给药相关生物屏障的策略。
Pharmaceutics. 2022 Jan 27;14(2):302. doi: 10.3390/pharmaceutics14020302.
6
Global Impact of Respiratory Disease: What Can We Do, Together, to Make a Difference?呼吸系统疾病的全球影响：我们能共同做些什么来产生影响？
Chest. 2022 May;161(5):1153-1154. doi: 10.1016/j.chest.2022.01.014. Epub 2022 Jan 17.
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Cost analysis of chronic obstructive pulmonary disease (COPD): a systematic review.慢性阻塞性肺疾病（COPD）的成本分析：一项系统综述。
Health Econ Rev. 2021 Aug 17;11(1):31. doi: 10.1186/s13561-021-00329-9.
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The Nanosystems Involved in Treating Lung Cancer.用于治疗肺癌的纳米系统。
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Nano Res. 2021;14(7):2067-2089. doi: 10.1007/s12274-020-3180-3. Epub 2021 Jan 8.
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Nanotechnology in pulmonary medicine.纳米技术在肺部医学中的应用。
Curr Opin Pharmacol. 2021 Feb;56:85-92. doi: 10.1016/j.coph.2020.11.002. Epub 2020 Dec 17.

用于呼吸系统疾病的药物递送系统：肺部给药治疗创新见解

Drug Delivery Systems for Respiratory Diseases: Insights into the Therapeutic Innovations for Pulmonary Administration.

作者信息

Govender Mershen, Choonara Yahya E

机构信息

Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg 2193, South Africa.

Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.

出版信息

Pharmaceutics. 2025 Apr 22;17(5):539. doi: 10.3390/pharmaceutics17050539.

DOI:10.3390/pharmaceutics17050539
PMID:40430832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12115048/
Abstract

Respiratory issues, such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, pulmonary hypertension, and respiratory infections, are amongst the most common and debilitating medical conditions experienced worldwide, affecting millions of patients annually [...].

摘要

呼吸系统疾病，如哮喘、慢性阻塞性肺疾病（COPD）、肺纤维化、肺动脉高压和呼吸道感染，是全球最常见且使人衰弱的医疗状况之一，每年影响数百万患者[……]