Berenson M M, Cardinal J R
Experientia. 1985 Oct 15;41(10):1328-30. doi: 10.1007/BF01952079.
Analog bile supersaturated with cholesterol was constituted, filtered and divided into equal portions containing no calcium or calcium, 2.5-15 mM. Aliquots were removed over the next 48 h and filtrates analyzed for cholesterol, bile acid and lecithin. Calcium accelerated cholesterol loss from solution in a dose-related fashion.
制备了胆固醇过饱和的模拟胆汁,过滤后分成不含钙或含钙(2.5 - 15 mM)的等份。在接下来的48小时内取出等分试样,对滤液进行胆固醇、胆汁酸和卵磷脂分析。钙以剂量相关的方式加速了溶液中胆固醇的损失。