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如何操作:机器人根治性远端胰腺脾切除术治疗胰腺体部交界性肿瘤中的标本分割与提起操作

How to do it: specimen splitting and lifting maneuver in robotic radical distal pancreatosplenectomy for borderline pancreatic body tumors.

作者信息

Fassari Alessia, De Blasi Vito, Rosso Edoardo

机构信息

Department of General Surgery, Centre Hospitalier de Luxembourg, 4 Rue Ernest Barblé, 1210, Luxembourg, Luxembourg.

Centre de Chirurgie Digestive, Pôle Santé Sud, 28 Rue de Guetteloup, 72100, Le Mans, France.

出版信息

Surg Today. 2025 May 28. doi: 10.1007/s00595-025-03065-3.

DOI:10.1007/s00595-025-03065-3
PMID:40434570
Abstract

Robotic radical pancreatosplenectomy is an advanced minimally invasive procedure for left-sided pancreatic cancer, especially for borderline tumors with suspected vascular involvement. Building on the oncologic principles of Radical Antegrade Modular Pancreatosplenectomy (RAMPS), we describe technical refinements tailored to the robotic setting. Specifically, our approach begins with early pancreatic transection to facilitate vascular exposure of bulky tumors, unlike with the classical RAMPS sequence, while preserving key principles such as posterior dissection and extended lymphadenectomy. Two cases are presented: one that required venous divestment and one that involved reconstruction of the splenomesenteric confluence using a bovine pericardial patch. The specimen-splitting and lifting maneuver enhances vascular control and visualization, enabling safer dissection and resection. Both procedures were completed robotically without conversion, achieving R0 margins, followed by uneventful recovery. While this technique diverges from Strasberg's original description, it aligns with its oncologic intent and reflects evolving surgical adaptations. Prospective data collection is ongoing to assess the long-term outcomes of complex cases.

摘要

机器人根治性胰脾切除术是一种针对左侧胰腺癌的先进微创手术,尤其适用于怀疑有血管受累的临界肿瘤。基于根治性顺行模块化胰脾切除术(RAMPS)的肿瘤学原则,我们描述了针对机器人手术环境的技术改进。具体而言,与经典的RAMPS顺序不同,我们的方法首先进行早期胰腺横断,以利于暴露体积较大肿瘤的血管,同时保留诸如后方解剖和扩大淋巴结清扫等关键原则。本文介绍了两例病例:一例需要静脉剥离,另一例涉及使用牛心包补片重建脾肠系膜汇合处。标本分割和提起操作增强了血管控制和可视化,使解剖和切除更安全。两台手术均通过机器人完成,未中转开腹,实现了R0切缘,随后恢复顺利。虽然该技术与斯特拉斯伯格最初的描述不同,但它符合其肿瘤学意图,并反映了不断发展的手术适应性。目前正在进行前瞻性数据收集,以评估复杂病例的长期结果。

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本文引用的文献

1
Huscher modified technique for robotic pancreaticojejunostomy: a video report.胡舍尔改良机器人胰空肠吻合术技术:视频报告
J Robot Surg. 2025 Jan 24;19(1):55. doi: 10.1007/s11701-025-02216-5.
2
Robotic pancreaticoduodenectomy for portal annular pancreas: how to do it.机器人辅助门静脉环形胰腺十二指肠切除术:如何实施
Surg Today. 2025 Jul;55(7):1004-1007. doi: 10.1007/s00595-024-02976-x. Epub 2024 Dec 23.
3
A comparison of pancreatojejunostomy using the modified Blumgart anastomosis with or without a four-needle three-loop suture device and continuous sutures for duct-to-mucosa anastomosis in robotic pancreaticoduodenectomy.
在机器人胰十二指肠切除术中,使用改良Blumgart吻合术进行胰空肠吻合时,比较有无四针三袢缝合装置以及连续缝合进行胰管-黏膜吻合的情况。
Surg Today. 2025 Mar;55(3):343-350. doi: 10.1007/s00595-024-02904-z. Epub 2024 Jul 30.
4
Short- and long-term outcomes of robotic versus open radical antegrade modular pancreatosplenectomy: a retrospective propensity score-matched cohort study.机器人与开放根治性顺行模块化胰脾切除术的短期和长期结果:回顾性倾向评分匹配队列研究。
Surg Endosc. 2024 Mar;38(3):1316-1328. doi: 10.1007/s00464-023-10635-4. Epub 2023 Dec 18.
5
Evaluating the learning curve of robotic radical antegrade modular pancreatosplenectomy: A retrospective cohort study.评估机器人根治性顺行模块化胰脾切除术的学习曲线:一项回顾性队列研究。
Int J Surg. 2022 May;101:106612. doi: 10.1016/j.ijsu.2022.106612. Epub 2022 Apr 18.
6
Role and Efficacy of Robotic-assisted Radical Antegrade Modular Pancreatosplenectomy (RAMPS) in Left-sided Pancreatic Cancer.机器人辅助顺行模块化胰脾切除术(RAMPS)在左侧胰腺癌中的作用及疗效
Cancer Diagn Progn. 2022 Mar 3;2(2):144-149. doi: 10.21873/cdp.10088. eCollection 2022 Mar-Apr.
7
A Systematic Review of Minimally Invasive Open Radical Antegrade Modular Pancreatosplenectomy for Pancreatic Cancer.微创经口胰前入路模块化胰脾切除术治疗胰腺癌的系统评价。
Anticancer Res. 2022 Feb;42(2):653-660. doi: 10.21873/anticanres.15523.
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Laparoscopic Radical Antegrade Modular Pancreatosplenectomy with Vascular Resection for Pancreatic Cancer: Tips and Tricks.腹腔镜下根治性顺行模块化胰脾切除术联合血管切除治疗胰腺癌:技巧与窍门。
J Gastrointest Surg. 2020 Dec;24(12):2896-2902. doi: 10.1007/s11605-020-04695-3. Epub 2020 Jul 14.
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Dig Surg. 2015;32(2):135-41. doi: 10.1159/000370008. Epub 2015 Mar 13.
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A safe technique for radical antegrade modular pancreatosplenectomy with venous resection for pancreatic cancer.一种用于胰腺癌伴静脉切除的根治性顺行模块化胰脾切除术的安全技术。
J Am Coll Surg. 2013 Nov;217(5):e35-9. doi: 10.1016/j.jamcollsurg.2013.08.007. Epub 2013 Sep 14.