Pham Vincent Q, Miller Hannah M, Fernandez Elise O, de Marchi Daniel, Budi Elizabeth, Zhu Hongtu, Fleischman David
Northeast Ohio Medical University, Rootstown, Ohio, United States of America.
Kittner Eye Center, University of North Carolina Hospitals, Chapel Hill, North Carolina, United States of America.
PLoS One. 2025 May 28;20(5):e0324821. doi: 10.1371/journal.pone.0324821. eCollection 2025.
The objective of this investigation is to evaluate the 5-year mortality of geriatric patients who have sustained eye injuries.
This retrospective cohort study included patients aged 65 years or older who had histories of either ocular trauma or age-related nuclear cataracts. Subjects and controls: Patients with ocular trauma constituted the study group, while those with a history of cataracts served as controls.
Data from the I2B2 Carolina Data Warehouse were analyzed. Patient demographics were collected, and the outcomes of interest were the overall mortality rate and annual mortality rates over a 5-year period. Chi-squared tests were utilized for the comparison of mortality data.
The primary outcomes were overall mortality rates and annual mortality rates expressed as percentages.
The study group consisted of 602 patients who had suffered ocular trauma. The control group included 1066 patients of similar age who had been diagnosed with age-related nuclear cataracts at some point in their lives. Among the study group, 74 patients died within 5 years, while 69 patients in the control group died within the same timeframe, resulting in a study group mortality rate of 11.30% and a control group mortality rate of 6.47%. For patients with ocular trauma, the annual mortality rates were 4.15%, 2.60%, 1.96%, 2.54%, and 0.56%, respectively. For the control group, the annual mortality rates were 1.03%, 1.70%, 1.64%, 0.88%, and 1.38% respectively.
The study suggests that geriatric patients who have experienced ocular trauma are at a higher risk of mortality compared to age-matched controls without such injuries. These findings highlight the necessity of identifying the causes of geriatric periorbital trauma and underscore the importance of close patient follow-up to improve outcomes.
本研究的目的是评估眼部受伤的老年患者的5年死亡率。
这项回顾性队列研究纳入了65岁及以上有眼外伤或年龄相关性核性白内障病史的患者。研究对象和对照组：眼外伤患者构成研究组，有白内障病史的患者作为对照组。
分析了I2B2卡罗来纳数据仓库的数据。收集了患者的人口统计学数据，感兴趣的结果是5年期间的总死亡率和年死亡率。采用卡方检验比较死亡率数据。
主要结局是以百分比表示的总死亡率和年死亡率。
研究组由602例眼外伤患者组成。对照组包括1066例年龄相仿、曾在生命中的某个时刻被诊断患有年龄相关性核性白内障的患者。研究组中有74例患者在5年内死亡，而对照组中有69例患者在同一时间段内死亡，研究组死亡率为11.30%，对照组死亡率为6.47%。眼外伤患者的年死亡率分别为4.15%、2.60%、1.96%、2.54%和0.56%。对照组的年死亡率分别为1.03%、1.70%、1.64%、0.88%和1.38%。
该研究表明，与未受此类损伤的年龄匹配对照组相比，经历过眼外伤的老年患者死亡风险更高。这些发现凸显了确定老年眶周创伤原因的必要性，并强调了密切随访患者以改善预后的重要性。
