Saarimaa H, Ojasalo T
J Int Med Res. 1985;13(4):236-40. doi: 10.1177/030006058501300407.
Nine patients suffering from cardiac insufficiency were given furosemide and two furosemide-triamterene combination products in random order. A statistically significant diuretic response was achieved with all these preparations. The combination of furosemide and triamterene brought about a 'softer' diuresis, no hypokalaemia and the advantage of dosage as only one tablet, thus eliminating the need for taking two separate drugs.
九名心脏功能不全患者被随机给予速尿以及两种速尿-氨苯蝶啶复方制剂。所有这些制剂均产生了具有统计学意义的利尿反应。速尿与氨苯蝶啶的复方制剂利尿作用“更温和”,不会导致低钾血症,且具有只需服用一片的剂量优势,从而无需分别服用两种药物。