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血液系统癌症患者的社会支持、应对策略、焦虑、抑郁和创伤后成长:一个结构方程模型

Hematological cancer patients' social support, coping strategies, anxiety, depression and posttraumatic growth: a structural equation model.

作者信息

Liang Taoyun, Mao Ling, Du Xinwen, Chen Fengjiao

机构信息

West China Hospital, Sichuan University, Chengdu, China.

出版信息

Front Oncol. 2025 May 14;15:1540973. doi: 10.3389/fonc.2025.1540973. eCollection 2025.

Abstract

OBJECTIVE

Posttraumatic growth (PTG), defined as positive psychological changes following traumatic events, has been observed in some hematological cancer patients during their disease course. These changes, encompassing shifts in life perspective, interpersonal relationships, and self-perception, are critical for psychological recovery. However, the interplay of social support, coping strategies, anxiety, and depression in shaping PTG remains unclear. Therefore, the aim of this study was to explore these associations in hematological cancer patients using a hypothetical model.

METHODS

From August 2019 to May 2021, a cross-sectional survey was conducted with 474 hospitalized patients with hematological cancer at West China Hospital, Sichuan University, China (a tertiary hospital). The Social Support Rating Scale, Medical Coping Modes Questionnaire, Hospital Anxiety and Depression Scale, and Posttraumatic Growth Inventory were used for data collection. Correlation and regression analyses were performed using SPSS 26.0, a structural equation model was constructed using AMOS 24.0 software, and the confidence interval of the mediating effect was calculated using the bias-corrected bootstrap method.

RESULTS

Social support was positively associated with PTG in hematological cancer patients ( = 0.564, = 0.004). Avoidance ( = 0.199, = 0.034) and acceptance-resignation ( = -0.315, = 0.002) coping strategies mediated this association, with depression ( = -0.123, = 0.009) further mediating the effects of coping strategies on PTG.

CONCLUSION

These findings provide a basis for further research on PTG in cancer patients, particularly with respect to coping strategies in various dimensions. Enhancing social support and addressing maladaptive coping may promote PTG. Tailored interventions targeting depression management and culturally sensitive support systems are recommended to enhance PTG.

摘要

目的

创伤后成长(PTG)被定义为创伤事件后产生的积极心理变化,在一些血液系统癌症患者的病程中已被观察到。这些变化包括生活观念、人际关系和自我认知的转变,对心理恢复至关重要。然而,社会支持、应对策略、焦虑和抑郁在塑造PTG过程中的相互作用仍不清楚。因此,本研究的目的是使用一个假设模型来探讨血液系统癌症患者中的这些关联。

方法

2019年8月至2021年5月,对中国四川大学华西医院(一家三级医院)的474例住院血液系统癌症患者进行了横断面调查。使用社会支持评定量表、医学应对方式问卷、医院焦虑抑郁量表和创伤后成长问卷进行数据收集。使用SPSS 26.0进行相关性和回归分析,使用AMOS 24.0软件构建结构方程模型,并使用偏差校正自助法计算中介效应的置信区间。

结果

社会支持与血液系统癌症患者的PTG呈正相关(=0.564,=0.004)。回避(=0.199,=0.034)和接受-屈服(=-0.315,=0.002)应对策略介导了这种关联,抑郁(=-0.123,=0.009)进一步介导了应对策略对PTG的影响。

结论

这些发现为进一步研究癌症患者的PTG提供了基础,特别是在各个维度的应对策略方面。加强社会支持和解决适应不良的应对方式可能会促进PTG。建议针对抑郁管理和文化敏感支持系统的定制干预措施,以增强PTG。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c74e/12116656/46696f560f26/fonc-15-1540973-g001.jpg

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