干燥综合征患者腮腺的磁共振涎腺造影和唾液腺SPECT/CT检查

Magnetic resonance sialography and salivary gland SPECT/CT for parotid glands in patients with Sjögren's syndrome.

作者信息

Shirai Ai, Nakatani Yuya, Toya Shuji, Ogura Ichiro

机构信息

Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Oral and Maxillofacial Surgery, Dry Mouth Clinic, The Nippon Dental University Niigata Hospital, Niigata, Japan.

出版信息

Dentomaxillofac Radiol. 2025 May 29. doi: 10.1093/dmfr/twaf048.

DOI:10.1093/dmfr/twaf048

PMID:40439152

Abstract

OBJECTIVE

The aim of this study was to investigate MR sialography and SPECT/CT for parotid glands in Sjögren's syndrome patients.

METHODS

Thirty Sjögren's syndrome patients underwent MR sialography and SPECT/CT. The MR sialographic stagings of Sjögren's syndrome were determined by the criteria (stage 0: normal; stage 1: punctate appearance; stage 2: globular appearance; stage 3: cavitary appearance; stage 4: destructive appearance). The maximum standardized uptake value (SUVmax) of the right and left parotid glands with SPECT/CT was obtained using a workstation and software. MR sialographic stagings and SUVmax of parotid glands were evaluated at pre- and post-stimulation and ratio of pre- to post-stimulation.

RESULTS

Regarding pre-stimulation, the SUVmax of stage 0 (31.9 ± 19.3) was significantly higher than that of stage 2 (19.7 ± 7.5, p = 0.046), stage 3 (10.2 ± 7.1, p < 0.001) and stage 4 (6.8 ± 4.3, p < 0.001). Furthermore, the SUVmax at ratio of pre- to post-stimulation of stage 0 (1.87 ± 0.55) was significantly higher than that of stage 3 (1.16 ± 0.30, p = 0.001) and stage 4 (1.16 ± 0.40, p < 0.001).

CONCLUSION

This study suggests that MR sialography and SPECT/CT SUV are effective tool for the management of Sjögren's syndrome patients.

摘要

目的

本研究旨在探讨磁共振涎腺造影（MR sialography）和单光子发射计算机断层显像/计算机断层扫描（SPECT/CT）在干燥综合征患者腮腺中的应用。

方法

30例干燥综合征患者接受了磁共振涎腺造影和SPECT/CT检查。干燥综合征的磁共振涎腺造影分期依据以下标准确定（0期：正常；1期：点状表现；2期：球状表现；3期：空洞状表现；4期：破坏状表现）。使用工作站和软件获取SPECT/CT检查时左右腮腺的最大标准化摄取值（SUVmax）。在刺激前和刺激后评估腮腺的磁共振涎腺造影分期和SUVmax以及刺激前与刺激后的比值。

结果

关于刺激前，0期的SUVmax（31.9±19.3）显著高于2期（19.7±7.5，p = 0.046）、3期（10.2±7.1，p < 0.001）和4期（6.8±4.3，p < 0.001）。此外，0期刺激前与刺激后比值的SUVmax（1.87±0.55）显著高于3期（1.16±0.30，p = 0.001）和4期（1.16±0.40，p < 0.001）。