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沙丁胺醇治疗后血浆高密度脂蛋白(HDL)水平的变化。

Changes in plasma high density lipoproteins (HDL) levels after salbutamol.

作者信息

Chazan R, Droszcz W, Bobilewicz D, Maruchin J E

出版信息

Int J Clin Pharmacol Ther Toxicol. 1985 Aug;23(8):427-9.

PMID:4044075
Abstract

Administration of salbutamol--in a single dose of 0.5 mg i.v. and in a dose of 8 mg twice daily during two weeks--was associated with an increase of HDL-cholesterol concentration in the serum of patients with chronic bronchitis and severe airway obstruction. At the end of the second week of oral treatment with salbutamol, the HDL-cholesterol concentration in serum increased by 6.9% (p less than 0.01).

摘要

沙丁胺醇的给药——静脉注射单剂量0.5毫克以及在两周内每日两次、每次剂量8毫克——与慢性支气管炎和严重气道阻塞患者血清中高密度脂蛋白胆固醇浓度的升高相关。在使用沙丁胺醇进行口服治疗的第二周结束时,血清中高密度脂蛋白胆固醇浓度升高了6.9%(p<0.01)。

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引用本文的文献

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Salbutamol in the Management of Asthma: A Review.沙丁胺醇在哮喘管理中的应用:综述。
Int J Mol Sci. 2022 Nov 17;23(22):14207. doi: 10.3390/ijms232214207.
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Salbutamol in the 1980s. A reappraisal of its clinical efficacy.20世纪80年代的沙丁胺醇。对其临床疗效的重新评估。
Drugs. 1989 Jul;38(1):77-122. doi: 10.2165/00003495-198938010-00004.
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Plasma and lipoprotein lipids and apolipoproteins AI, AII and B in patients with chronic airflow limitation.慢性气流受限患者的血浆及脂蛋白脂质与载脂蛋白AI、AII和B
J R Soc Med. 1989 Feb;82(2):91-2. doi: 10.1177/014107688908200212.