Song Gee Youn
Department of Family Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
Korean J Fam Med. 2025 May;46(3):195-203. doi: 10.4082/kjfm.25.0085. Epub 2025 May 20.
Obesity, sarcopenia, and sarcopenic obesity are increasingly prevalent in older adults and negatively affect health-related quality of life (HRQOL). While EuroQol-5 Dimension and Short Form-36 Health Survey are widely used HRQOL measures, they have limitations in sensitivity and cultural relevance. In contrast, the Health-related Quality of Life Instrument with 8 Items (HINT-8) is a preference-based instrument developed specifically for the Korean population, offering finer discrimination of physical, emotional, and social health domains.
This study analyzed data from 1,387 older adults (≥65 years) from the 2023 Korea National Health and Nutrition Examination Survey. Obesity was defined as body mass index ≥25 kg/m 2 , sarcopenia by Asian Working Group for Sarcopenia 2019 criteria, and sarcopenic obesity as having both conditions. Multiple linear regression was used to examine their independent effects on HRQOL, adjusting for potential confounders.
Of the participants, 54.2% were classified as normal, 34.9% as obese, 9.8% with sarcopenia, and 1.1% with sarcopenic obesity. All three conditions were significantly associated with greater difficulty in stair climbing: obesity (B=0.223, P<0.001), sarcopenia (B=0.242, P<0.001), and sarcopenic obesity (B=0.338, P=0.048). Sarcopenia was also linked to impaired working ability and higher total HINT-8 scores. Sarcopenic obesity was associated with greater pain. And obesity was linked to slightly lower depression scores.
Obesity, sarcopenia, and sarcopenic obesity negatively impact HRQOL in older adults. Early detection and intervention are essential to improve quality of life and extend health-adjusted life expectancy.
肥胖、肌肉减少症和肌肉减少性肥胖在老年人中越来越普遍,并对健康相关生活质量(HRQOL)产生负面影响。虽然欧洲五维健康量表(EuroQol-5 Dimension)和健康调查简表36(Short Form-36 Health Survey)是广泛使用的HRQOL测量工具,但它们在敏感性和文化相关性方面存在局限性。相比之下,8项健康相关生活质量量表(Health-related Quality of Life Instrument with 8 Items,HINT-8)是一种基于偏好的量表,专为韩国人群开发,能够更精细地区分身体、情感和社会健康领域。
本研究分析了2023年韩国国民健康与营养检查调查中1387名65岁及以上老年人的数据。肥胖定义为体重指数≥25kg/m²,肌肉减少症根据亚洲肌肉减少症工作组2019年标准定义,肌肉减少性肥胖定义为同时患有这两种疾病。采用多元线性回归分析它们对HRQOL的独立影响,并对潜在混杂因素进行校正。
在参与者中,54.2%被分类为正常,34.9%为肥胖,9.8%患有肌肉减少症,1.1%患有肌肉减少性肥胖。所有这三种情况都与爬楼梯困难程度增加显著相关:肥胖(B=0.223,P<0.001)、肌肉减少症(B=0.242,P<0.001)和肌肉减少性肥胖(B=0.338,P=0.048)。肌肉减少症还与工作能力受损和较高的HINT-8总分相关。肌肉减少性肥胖与更严重的疼痛有关。而肥胖与略低的抑郁评分有关。
肥胖、肌肉减少症和肌肉减少性肥胖对老年人的HRQOL有负面影响。早期发现和干预对于提高生活质量和延长健康调整寿命至关重要。