Xu Ran, Wang Xin-Jun, Lin Qing-Cheng, Zhuang Yan-Ting, Zhou Qing-Ying, Xu Nai-Fen, Zheng Ding-Qin
Department of Urology, Pingyang Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Department of Urology, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, People's Republic of China.
Risk Manag Healthc Policy. 2025 May 24;18:1721-1733. doi: 10.2147/RMHP.S506211. eCollection 2025.
Over the past three decades, male infertility has become a significant burden on global public health. As an international organization with nearly half of the world's population, BRICS plays a crucial role in global health. This study investigates the trend of male infertility burden in BRICS countries from 1990 to 2021, providing valuable information for prevention and treatment strategies.
Data on male infertility in BRICS countries were obtained from the Global Burden of Disease database. Joinpoint regression, decomposition analysis, and prediction models were applied to analyze the data and assess the disease burden trends.
The global prevalence of male infertility has worsened significantly between 1990 and 2021, with projections indicating this trend will continue for the next 15 years. While this global trend is based on data from a range of countries, the results of this study specifically focus on the BRICS countries. In these countries, while China and the Russian Federation have had high prevalence rates, improvements were observed over the past 30 years. India and Brazil, though unable to control male infertility in this period, have managed to halt its worsening in recent years. South Africa experienced substantial fluctuations from 2001 to 2015, with further significant changes projected in the next 15 years.
This study provides valuable insights into the evolving burden of male infertility in BRICS countries. It underscores the importance of targeted prevention and treatment strategies for these countries based on national and global trends.
在过去三十年中，男性不育已成为全球公共卫生的一项重大负担。金砖国家作为一个拥有世界近一半人口的国际组织，在全球卫生中发挥着关键作用。本研究调查了1990年至2021年金砖国家男性不育负担的趋势，为预防和治疗策略提供了有价值的信息。
金砖国家男性不育的数据来自全球疾病负担数据库。采用Joinpoint回归、分解分析和预测模型对数据进行分析，并评估疾病负担趋势。
1990年至2021年期间，全球男性不育患病率显著恶化，预测表明这一趋势在未来15年将持续。虽然这一全球趋势基于一系列国家的数据，但本研究结果特别关注金砖国家。在这些国家中，中国和俄罗斯联邦患病率一直较高，但在过去30年中有所改善。印度和巴西虽然在此期间未能控制男性不育，但近年来已设法阻止其恶化。南非在2001年至2015年期间经历了大幅波动，预计未来15年还会有进一步的显著变化。
本研究为金砖国家男性不育负担的演变提供了有价值的见解。它强调了根据国家和全球趋势为这些国家制定有针对性的预防和治疗策略的重要性。
