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不止于皮肤表面:将慢性炎症性皮肤病重新定义为一种全身性威胁。

Not just skin deep: reframing chronic inflammatory skin disease as a systemic threat.

作者信息

Smith Annika, Chow Clara K

机构信息

Department of Dermatology, Westmead Hospital, Sydney, New South Wales, Australia.

Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.

出版信息

Intern Med J. 2025 Jul;55(7):1193-1197. doi: 10.1111/imj.70088. Epub 2025 May 30.

DOI:10.1111/imj.70088
PMID:40446064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12240009/
Abstract

Chronic inflammatory skin disease is more than skin deep, with several cutaneous disease entities associated with an increased risk of cardiovascular disease. Notably, psoriasis carries a markedly increased risk of cardiovascular disease, along with a significant comorbid burden. There is a need for greater clinician, patient and community awareness around the impact of chronic cutaneous inflammation, with attention to psoriasis in particular, in order to enhance care in this cohort.

摘要

慢性炎症性皮肤病的影响不止于皮肤表面,多种皮肤疾病实体都与心血管疾病风险增加相关。值得注意的是,银屑病患者患心血管疾病的风险显著增加,同时还伴有严重的合并症负担。临床医生、患者和社区需要进一步认识慢性皮肤炎症的影响,尤其是银屑病,以便加强对这一群体的护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e0/12240009/eee4a598e4c6/IMJ-55-1193-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e0/12240009/42396fd69ab8/IMJ-55-1193-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e0/12240009/eee4a598e4c6/IMJ-55-1193-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e0/12240009/42396fd69ab8/IMJ-55-1193-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e0/12240009/eee4a598e4c6/IMJ-55-1193-g002.jpg

相似文献

1
Not just skin deep: reframing chronic inflammatory skin disease as a systemic threat.不止于皮肤表面:将慢性炎症性皮肤病重新定义为一种全身性威胁。
Intern Med J. 2025 Jul;55(7):1193-1197. doi: 10.1111/imj.70088. Epub 2025 May 30.
2
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本文引用的文献

1
Improving Cardiovascular Outcomes in the Psoriasis Cohort. Psoriasis and Cardiovascular Disease-Clinician Knowledge, Practice and Perceptions.改善银屑病患者群体的心血管结局。银屑病与心血管疾病——临床医生的知识、实践与认知。
Australas J Dermatol. 2025 Jun;66(4):e187-e196. doi: 10.1111/ajd.14436. Epub 2025 Feb 22.
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Managing the Patient with Psoriasis and Metabolic Comorbidities.管理合并代谢性合并症的银屑病患者。
Am J Clin Dermatol. 2024 Jul;25(4):527-540. doi: 10.1007/s40257-024-00857-0. Epub 2024 May 15.
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Psoriasis Increased the Risk of Adverse Cardiovascular Outcomes: A New Systematic Review and Meta-Analysis of Cohort Study.
银屑病增加不良心血管结局风险:一项新的队列研究系统评价与荟萃分析
Front Cardiovasc Med. 2022 Mar 25;9:829709. doi: 10.3389/fcvm.2022.829709. eCollection 2022.
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Current Concepts of Psoriasis Immunopathogenesis.当前银屑病发病机制的免疫学概念。
Int J Mol Sci. 2021 Oct 26;22(21):11574. doi: 10.3390/ijms222111574.
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Psoriasis: a brief overview.银屑病:简要概述。
Clin Med (Lond). 2021 May;21(3):170-173. doi: 10.7861/clinmed.2021-0257.
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Impact of Biological Agents on Imaging and Biomarkers of Cardiovascular Disease in Patients with Psoriasis: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.生物制剂对银屑病患者心血管疾病影像学和生物标志物的影响:一项随机安慰剂对照试验的系统评价和荟萃分析。
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J Am Coll Cardiol. 2021 Apr 6;77(13):1670-1680. doi: 10.1016/j.jacc.2021.02.009.
8
Chronic Systemic Inflammatory Skin Disease as a Risk Factor for Cardiovascular Disease.慢性系统性炎症性皮肤病作为心血管疾病的一个危险因素。
Curr Probl Cardiol. 2021 May;46(5):100799. doi: 10.1016/j.cpcardiol.2021.100799. Epub 2021 Jan 24.
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National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study.银屑病的国家、地区和全球流行病学:系统分析和建模研究。
BMJ. 2020 May 28;369:m1590. doi: 10.1136/bmj.m1590.
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Adv Ther. 2020 May;37(5):2017-2033. doi: 10.1007/s12325-020-01346-6. Epub 2020 Apr 20.