Martins Olga Beatriz Lopes, Fernandes Ighor Andrade, de Souza Glaciele Maria, Gonçalves Patricia Furtado, Falci Saulo Gabriel Moreira, Galvão Endi Lanza
Department of Dentistry, School of Biological and Health Sciences, Universidade Federal Dos Vales Do Jequitinhonha E Mucuri, Diamantina, MG, Brazil.
Department of Physical Therapy, School of Biological and Health Sciences, Universidade Federal Dos Vales Do Jequitinhonha E Mucuri, Diamantina, MG, Brazil.
Oral Maxillofac Surg. 2025 Jun 1;29(1):114. doi: 10.1007/s10006-025-01407-6.
This study aimed to evaluate the impact of maxillofacial fractures (MFFs) on health-related quality of life (HRQoL) and oral health-related quality of life (OHRQoL).
A systematic literature review was carried out following the MOOSE and PRISMA guidelines. The search was conducted in LILACS, Embase, and PubMed databases alongside manual reference checks, with no date restrictions, including observational studies that assessed HRQoL or OHRQoL in patients with MFFs using validated instruments. Methodological quality was assessed using the JBI checklist.
Twelve studies were included in the analysis, most with a cohort design and male predominance. The results indicated a negative impact of MFFs on HRQoL, especially in the immediate post-traumatic period/immediately after MFF diagnosis, with impairment in domains such as pain, physical function, mental health, and social aspects. OHRQoL was also affected, mainly regarding pain, chewing difficulty, and dietary changes. Although most studies indicated improved quality of life after treatment and recovery, long-term sequelae, such as infraorbital nerve paresthesia, may persist. The review showed heterogeneity among studies regarding geographical origin, methodological design, follow-up periods, and quality of life assessment instruments. Small sample sizes, lack of detailed analysis of socioeconomic and health factors, inadequate control of variables, and the predominance of male patients in some studies limit the generalizability of the findings.
MFFs seem to affect patients' HRQoL and OHRQoL, but further longitudinal studies with larger samples and standardized assessments are needed to deepen the understanding of the long-term impact.
本研究旨在评估颌面骨折(MFFs)对健康相关生活质量(HRQoL)和口腔健康相关生活质量(OHRQoL)的影响。
按照MOOSE和PRISMA指南进行系统的文献综述。在拉丁美洲和加勒比地区卫生科学数据库(LILACS)、荷兰医学文摘数据库(Embase)和美国国立医学图书馆生物医学文献数据库(PubMed)中进行检索,并进行人工参考文献核对,无日期限制,纳入使用经过验证的工具评估MFFs患者HRQoL或OHRQoL的观察性研究。使用JBI检查表评估方法学质量。
12项研究纳入分析,大多数采用队列设计且男性占主导。结果表明,MFFs对HRQoL有负面影响,尤其是在创伤后即刻/MFF诊断后即刻,在疼痛、身体功能、心理健康和社会方面等领域存在损害。OHRQoL也受到影响,主要涉及疼痛、咀嚼困难和饮食变化。尽管大多数研究表明治疗和康复后生活质量有所改善,但长期后遗症,如眶下神经感觉异常,可能会持续存在。综述显示,研究在地理来源、方法学设计、随访期和生活质量评估工具方面存在异质性。样本量小、缺乏对社会经济和健康因素的详细分析、变量控制不足以及部分研究中男性患者占主导限制了研究结果的普遍性。
MFFs似乎会影响患者的HRQoL和OHRQoL,但需要进一步开展更大样本量和标准化评估的纵向研究,以加深对长期影响的理解。