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肾上腺神经鞘瘤:肾上腺肿瘤中一种罕见但重要的考虑因素。

Adrenal Schwannoma: A Rare but Important Consideration in Adrenal Tumors.

作者信息

Hamid Tariq Abdul, Yaser Khawla, Abo Alsel Khaldon, Alhayek Rafe, Saeedi Yaser

机构信息

Surgery, Dubai Health, Dubai, ARE.

Urology, Dubai Health, Dubai, ARE.

出版信息

Cureus. 2025 May 1;17(5):e83282. doi: 10.7759/cureus.83282. eCollection 2025 May.

DOI:10.7759/cureus.83282
PMID:40452686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12126914/
Abstract

Adrenal schwannomas (AS) are rare and are often detected incidentally on imaging studies. Due to their nonspecific imaging characteristics and typically normal endocrine profiles, definitive diagnosis relies on histopathological examination. This case report presents a 72-year-old male patient with a 4.6 cm right adrenal mass, initially suspected to be an adrenal adenoma on ultrasound. A contrast-enhanced computed tomography (CT) scan later characterized the lesion as a well-defined, heterogeneous, loculated mass with an absolute washout of 40% and a relative washout of 18.2%, raising concerns about its malignant potential. Endocrine evaluation confirmed its nonfunctional nature. Given its increasing size and unclear nature, surgical excision via robot-assisted transperitoneal adrenalectomy was performed. Histopathological and immunohistochemical analyses confirmed the diagnosis of a benign adrenal schwannoma. This case highlights the diagnostic challenges and therapeutic approach to AS, emphasizing the role of surgical resection in managing adrenal incidentalomas with indeterminate malignant potential.

摘要

肾上腺神经鞘瘤(AS)较为罕见,常在影像学检查时偶然发现。由于其影像学特征不具特异性且内分泌指标通常正常,明确诊断依赖于组织病理学检查。本病例报告介绍了一名72岁男性患者,其右侧肾上腺有一个4.6厘米的肿块,超声检查最初怀疑为肾上腺腺瘤。随后的增强计算机断层扫描(CT)显示该病变为边界清晰、不均匀、有分隔的肿块,绝对廓清率为40%,相对廓清率为18.2%,引发了对其恶性潜能的担忧。内分泌评估证实其无功能。鉴于其体积增大且性质不明,遂通过机器人辅助经腹肾上腺切除术进行手术切除。组织病理学和免疫组织化学分析确诊为良性肾上腺神经鞘瘤。本病例突出了肾上腺神经鞘瘤的诊断挑战和治疗方法,强调了手术切除在处理具有不确定恶性潜能的肾上腺意外瘤中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/b34da58d4b7a/cureus-0017-00000083282-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/6e9ba43e3c14/cureus-0017-00000083282-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/b61e5c2c19ae/cureus-0017-00000083282-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/dd2a2d61c18c/cureus-0017-00000083282-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/b34da58d4b7a/cureus-0017-00000083282-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/6e9ba43e3c14/cureus-0017-00000083282-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/b61e5c2c19ae/cureus-0017-00000083282-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/dd2a2d61c18c/cureus-0017-00000083282-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/12126914/b34da58d4b7a/cureus-0017-00000083282-i04.jpg

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本文引用的文献

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Rare adrenal schwannoma treated with robotic-assisted adrenalectomy: A case report.机器人辅助肾上腺切除术治疗罕见肾上腺神经鞘瘤:一例报告
Urol Case Rep. 2024 Jul 22;56:102807. doi: 10.1016/j.eucr.2024.102807. eCollection 2024 Sep.
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Adrenal and periadrenal schwannoma: histological, molecular and clinical characterization of an institutional case series.肾上腺和肾上腺周围神经鞘瘤:机构病例系列的组织学、分子和临床特征。
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肾上腺手术后的一项不寻常发现:肾上腺神经鞘瘤病例系列
Front Surg. 2023 May 24;10:1175633. doi: 10.3389/fsurg.2023.1175633. eCollection 2023.
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A Rare Presentation of Polygenic Inheritance Manifesting As Congenital Rubella Syndrome: A Case Report.表现为先天性风疹综合征的多基因遗传罕见病例报告
Cureus. 2022 Dec 23;14(12):e32861. doi: 10.7759/cureus.32861. eCollection 2022 Dec.
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BJR Case Rep. 2020 Feb 12;6(1):20190044. doi: 10.1259/bjrcr.20190044. eCollection 2020 Mar.
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