Hamid Tariq Abdul, Yaser Khawla, Abo Alsel Khaldon, Alhayek Rafe, Saeedi Yaser
Surgery, Dubai Health, Dubai, ARE.
Urology, Dubai Health, Dubai, ARE.
Cureus. 2025 May 1;17(5):e83282. doi: 10.7759/cureus.83282. eCollection 2025 May.
Adrenal schwannomas (AS) are rare and are often detected incidentally on imaging studies. Due to their nonspecific imaging characteristics and typically normal endocrine profiles, definitive diagnosis relies on histopathological examination. This case report presents a 72-year-old male patient with a 4.6 cm right adrenal mass, initially suspected to be an adrenal adenoma on ultrasound. A contrast-enhanced computed tomography (CT) scan later characterized the lesion as a well-defined, heterogeneous, loculated mass with an absolute washout of 40% and a relative washout of 18.2%, raising concerns about its malignant potential. Endocrine evaluation confirmed its nonfunctional nature. Given its increasing size and unclear nature, surgical excision via robot-assisted transperitoneal adrenalectomy was performed. Histopathological and immunohistochemical analyses confirmed the diagnosis of a benign adrenal schwannoma. This case highlights the diagnostic challenges and therapeutic approach to AS, emphasizing the role of surgical resection in managing adrenal incidentalomas with indeterminate malignant potential.
肾上腺神经鞘瘤(AS)较为罕见,常在影像学检查时偶然发现。由于其影像学特征不具特异性且内分泌指标通常正常,明确诊断依赖于组织病理学检查。本病例报告介绍了一名72岁男性患者,其右侧肾上腺有一个4.6厘米的肿块,超声检查最初怀疑为肾上腺腺瘤。随后的增强计算机断层扫描(CT)显示该病变为边界清晰、不均匀、有分隔的肿块,绝对廓清率为40%,相对廓清率为18.2%,引发了对其恶性潜能的担忧。内分泌评估证实其无功能。鉴于其体积增大且性质不明,遂通过机器人辅助经腹肾上腺切除术进行手术切除。组织病理学和免疫组织化学分析确诊为良性肾上腺神经鞘瘤。本病例突出了肾上腺神经鞘瘤的诊断挑战和治疗方法,强调了手术切除在处理具有不确定恶性潜能的肾上腺意外瘤中的作用。